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  2. Is Sildenafil Safe for This Common Male Problem? - AOL

    www.aol.com/sildenafil-safe-common-male-problem...

    Sildenafil is most commonly prescribed to be taken one time per day in doses between 25 and 100 mg for ED. Your healthcare provider will determine the best dosage for you based on a number of factors.

  3. How to Take Viagra for Best Results - AOL

    www.aol.com/viagra-best-results-105700318.html

    How to Use Viagra for Best Results. Viagra is great as an ED treatment, but taking it in particular conditions can make it even more effective. To get the best results from Viagra when treating ...

  4. Your ED Pill Guide: Everything You Need to Know Before ... - AOL

    www.aol.com/ed-pill-guide-everything-know...

    Viagra (or sildenafil) lasts three to five hours after it’s consumed. Cialis (tadalafil) has a half-life of 17.5 hours, meaning this drug lasts up to 36 hours after it’s consumed.

  5. PDE5 inhibitor - Wikipedia

    en.wikipedia.org/wiki/PDE5_inhibitor

    Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.

  6. Sildenafil - Wikipedia

    en.wikipedia.org/wiki/Sildenafil

    This metabolite also has an affinity for the PDE receptors, about 40% of that of sildenafil. Thus, the metabolite is responsible for about 20% of sildenafil's action. Sildenafil is excreted as metabolites predominantly in the feces (about 80% of administered oral dose) and to a lesser extent in the urine (around 13% of the administered oral dose).

  7. Homosildenafil - Wikipedia

    en.wikipedia.org/wiki/Homosildenafil

    Homosildenafil (also known as methyl-sildenafil) is a synthetic drug which acts as a phosphodiesterase inhibitor. [1] It is an analog of sildenafil and vardenafil . Homosildenafil was first identified as an adulterant in sex enhancement products in 2003 and was more recently detected in dietary supplements.

  8. Do You Know What Viagra Was Originally Used For? (Plus What ...

    www.aol.com/viagra-treats-side-effects-plus...

    Benefits of Viagra: What Does Sildenafil Do for Men? Plenty of claims have been made about the health benefits of Viagra for men. Sildenafil’s ability to increase blood flow makes the medication ...

  9. Herbal Viagra: What Is It & Is It Safe? - AOL

    www.aol.com/herbal-viagra-safe-115700577.html

    Viagra is the brand-name version of a medication called sildenafil citrate. It belongs to a class of drugs called phosphodiesterase 5 inhibitors, more commonly known as PDE5 inhibitors.

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