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  2. Electrophilic fluorination - Wikipedia

    en.wikipedia.org/wiki/Electrophilic_fluorination

    The mechanism of electrophilic fluorination remains controversial. At issue is whether the reaction proceeds via an S N 2 or single-electron transfer (SET) process. In support of the S N 2 mechanism, aryl Grignard reagents and aryllithiums give similar yields of fluorobenzene in combination with N-fluoro-o-benzenedisulfonimide (NFOBS), even though the tendencies of these reagents to ...

  3. Selectfluor - Wikipedia

    en.wikipedia.org/wiki/Selectfluor

    Electrophilic fluorinating reagents could in principle operate by electron transfer pathways or an S N 2 attack at fluorine. This distinction has not been decided. [2] By using a charge-spin separated probe, [3] it was possible to show that the electrophilic fluorination of stilbenes with Selectfluor proceeds through an SET/fluorine atom transfer mechanism.

  4. Organofluorine chemistry - Wikipedia

    en.wikipedia.org/wiki/Organofluorine_chemistry

    Starting in the late 1940s, a series of electrophilic fluorinating methodologies were introduced, beginning with CoF 3. Electrochemical fluorination ("electrofluorination") was announced, which Joseph H. Simons had developed in the 1930s to generate highly stable perfluorinated materials compatible with uranium hexafluoride. [15]

  5. Electrochemical fluorination - Wikipedia

    en.wikipedia.org/wiki/Electrochemical_fluorination

    Electrochemical fluorination (ECF), or electrofluorination, is a foundational organofluorine chemistry method for the preparation of fluorocarbon-based organofluorine compounds. [1] The general approach represents an application of electrosynthesis .

  6. Perfluorobutanesulfonyl fluoride - Wikipedia

    en.wikipedia.org/wiki/Perfluorobutanesulfonyl...

    As mentioned above, aryl and alkenyl nonaflates are useful as electrophiles in palladium catalyzed cross coupling reactions. Their reactivity generally mirrors that of the more commonly encountered triflate electrophiles, but nonaflates tend to be less prone to hydrolysis to ketones (in the case of alkenyl sulfonates) and phenols (in the case of aryl sulfonates).

  7. Radical fluorination - Wikipedia

    en.wikipedia.org/wiki/Radical_fluorination

    Radical fluorination is a type of fluorination reaction, complementary to nucleophilic and electrophilic approaches. [1] It involves the reaction of an independently generated carbon-centered radical with an atomic fluorine source and yields an organofluorine compound .

  8. Electrophilic halogenation - Wikipedia

    en.wikipedia.org/wiki/Electrophilic_halogenation

    Halogenation of benzene where X is the halogen, catalyst represents the catalyst (if needed) and HX represents the protonated base. A few types of aromatic compounds, such as phenol , will react without a catalyst , but for typical benzene derivatives with less reactive substrates, a Lewis acid is required as a catalyst .

  9. Thomas Lectka - Wikipedia

    en.wikipedia.org/wiki/Thomas_Lectka

    He conducted research on the chemistry of [C-F-C] fluoronium ions [16] and later reported first spectroscopic evidence for fluoronium ions in a solution. [17] Lectka has also worked on metal-catalyzed aliphatic fluorination [ 18 ] and site-selective aliphatic fluorination.

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