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Results released in February 2009 from a clinical trial of PRO 2000 (Indevus Pharmaceuticals), a vaginal-microbicide gel (0.5%), sparked hope that it might provide modest protection against HIV. [22] The results of a larger trial released in December 2009 showed that PRO 2000 was safe as administered, but was ineffective in reducing the risk of ...
Nonoxynol-9 is a common ingredient of most vaginal and anal lubricants due to its spermicidal properties. A 2004 study found that over a six-month period, the typical-use failure rates for five nonoxynol-9 vaginal contraceptives (film, suppository, and gels at three different concentrations) ranged from 10% to 20%.
Vaginal lubrication fluid is a plasma transudate which diffuses across the vaginal wall. Composition varies with the length of arousal. [1]During arousal, vaginal lubrication, also sometimes called "arousal fluid", is produced.
K-Y Jelly was initially used as a surgical lubricant before it gained popularity as a personal lubricant. [citation needed] Lignocaine gel containing the local anaesthetic lignocaine is a prime example of a non-irritating substances used as surgical lubricant [citation needed] Medicinal castor oil was the original vegetable-based surgical ...
Hydroxyethyl cellulose can be one of the main ingredients in water-based personal lubricants. It is also a key ingredient in the formation of large bubbles as it possesses the ability to dissolve in water but also provide structural strength to the soap bubble. Among other similar chemicals, it is often used as slime (and gunge, in the UK).
April 21, 2022 at 4:38 PM. ... There’s also the Power Trip kit that features two bestselling vibrators and a water based lube. And there’s no risk—the brand promises 60-day returns for store ...
Consistency and viscosity affect the adhesion and retention property of the gel, and are important in ensuring the gel is retained at the site of application and effective delivery of the drug. [ 3 ] The ingredients in topical gel formulation can be broadly categorized into four types: gelator, solvent, drug, and excipients.
HPC is also used as a lubricant for artificial eyes. [2] [3] [4] HPC is used as a thickener, a low level binder and as an emulsion stabiliser with E number E463. In pharmaceuticals it is used as a binder [5] in tablets. HPC is used as a sieving matrix for DNA separations by capillary and microchip electrophoresis. [6]
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