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  2. Celecoxib - Wikipedia

    en.wikipedia.org/wiki/Celecoxib

    Celecoxib, sold under the brand name Celebrex among others, is a COX-2 inhibitor and nonsteroidal anti-inflammatory drug (NSAID). [7] It is used to treat the pain and inflammation in osteoarthritis, acute pain in adults, rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, painful menstruation, and juvenile rheumatoid arthritis. [7]

  3. Cyclooxygenase-2 inhibitor - Wikipedia

    en.wikipedia.org/wiki/Cyclooxygenase-2_inhibitor

    In the CLASS trial which compared Celebrex 800 mg/day to ibuprofen 2400 mg/day and diclofenac 150 mg/day for osteoarthritis or rheumatoid arthritis for six months, Celebrex was associated with significantly fewer upper gastrointestinal complications (0.44% vs. 1.27%, p = 0.04), with no significant difference in incidence of cardiovascular ...

  4. Discovery and development of cyclooxygenase 2 inhibitors

    en.wikipedia.org/wiki/Discovery_and_development...

    It was developed for the treatment of osteoarthritis, rheumatoid arthritis and acute pain. The acidic nature of lumiracoxib allows it to penetrate well into areas of inflammation. It has shown to be rapidly and well absorbed, with peak plasma concentration occurring in about 1–3 hours. [17]

  5. Acupuncture can help relieve sciatica pain, new ... - AOL

    www.aol.com/acupuncture-help-relieve-sciatica...

    Acupuncture successfully reduced pain and disability for people with chronic sciatica in a randomized clinical trial in China. Their improvement, compared to those receiving sham acupuncture ...

  6. Say Goodbye To Sciatica Pain By Stretching These Two Muscles

    www.aol.com/goodbye-sciatica-pain-stretching-two...

    4. Figure Four Seated Stretch. How to: Sit on a chair with feet flat on ground. Cross right ankle leg over left thigh. Keep spine straight and hinge forward to feel a stretch in glute and hip.

  7. The best muscle pain relief creams of 2025, according to ...

    www.aol.com/lifestyle/best-muscle-pain-relief...

    The topical cream can be used to relieve back pain, minor arthritis and muscle and joint pain. A 4-ounce tube retails for around $8 so it's pretty affordable, plus, it has great reviews.

  8. Nonsteroidal anti-inflammatory drug - Wikipedia

    en.wikipedia.org/wiki/Nonsteroidal_anti...

    Pain following surgery can be significant, and many people require strong pain medications such as opioids. There is some low-certainty evidence that starting NSAID painkiller medications in adults early, before surgery, may help reduce post-operative pain, and also reduce the dose or quantity of opioid medications required after surgery. [ 29 ]

  9. Dealing With Sciatica? Experts Say These Mattresses Can ... - AOL

    www.aol.com/dealing-sciatica-experts-mattresses...

    In simple terms, sciatica is a pain that radiates along the sciatic nerve, the longest nerve in the human body. It runs from the lower back down through the buttocks and into the legs and feet.

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