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Ferritin is found in most tissues as a cytosolic protein, but small amounts are secreted into the serum where it functions as an iron carrier. Plasma ferritin is also an indirect marker of the total amount of iron stored in the body; hence, serum ferritin is used as a diagnostic test for iron-deficiency anemia and iron overload. [4]
434624 Ensembl ENSG00000087086 n/a UniProt P02792 n/a RefSeq (mRNA) NM_000146 n/a RefSeq (protein) NP_000137 n/a Location (UCSC) Chr 19: 48.97 – 48.97 Mb n/a PubMed search Wikidata View/Edit Human View/Edit Mouse Ferritin light chain is a protein that in humans is encoded by the FTL gene. Ferritin is the major protein responsible for storing intracellular iron in prokaryotes and eukaryotes ...
Neuroferritinopathy is a genetic neurodegenerative disorder characterized by the accumulation of iron in the basal ganglia, cerebellum, and motor cortex of the human brain. . Symptoms, which are extrapyramidal in nature, progress slowly and generally do not become apparent until adulthood
Iron is both necessary to the body and potentially toxic. Controlling iron levels in the body is a critically important part of many aspects of human health and disease. Hematologists have been especially interested in systemic iron metabolism, because iron is essential for red blood cells, where most of the human body's iron is contained.
14319 Ensembl ENSG00000167996 ENSMUSG00000024661 UniProt P02794 P09528 RefSeq (mRNA) NM_002032 NM_010239 RefSeq (protein) NP_002023 NP_034369 Location (UCSC) Chr 11: 61.96 – 61.97 Mb Chr 19: 9.96 – 9.96 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Ferritin heavy chain is a ferroxidase enzyme that in humans is encoded by the FTH1 gene. FTH1 gene is located on chromosome 11, and ...
The Mayo Clinic diet, a program that adheres to this notion, was developed by medical professionals based on scientific research, so you can trust that this program is based on science, and not ...
Iron-binding proteins are carrier proteins and metalloproteins that are important in iron metabolism [1] and the immune response. [2] [3] Iron is required for life.Iron-dependent enzymes catalyze a variety of biochemical reactions and can be divided into three broad classes depending on the structure of their active site: non-heme mono-iron, non-heme diiron , or heme centers. [4]
The ideal is to increase the body's iron deposits, measured as levels of ferritin in serum, with the aim of reaching a ferritin value between 30 and 100 ng/mL. A clinical study has shown an increase in ferritin levels in those taking iron compared with others receiving a placebo. [11]
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related to: what is ferritin protein good for the body in adults mayo clinic chart access