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Multiple sclerosis (MS) is an autoimmune disease resulting in damage to the insulating covers of nerve cells in the brain and spinal cord. [3] As a demyelinating disease , MS disrupts the nervous system's ability to transmit signals , resulting in a range of signs and symptoms , including physical, mental , and sometimes psychiatric problems.
These conditions, where the body's immune system mistakenly attacks its own cells, affect a range of organs and systems within the body. Each disorder is listed with the primary organ or body part that it affects and the associated autoantibodies that are typically found in people diagnosed with the condition. Each disorder is also categorized ...
Main symptoms of multiple sclerosis Symptoms and findings in multiple sclerosis. Multiple sclerosis can cause a variety of symptoms varying significantly in severity and progression among individuals: changes in sensation (hypoesthesia), muscle weakness, abnormal muscle spasms, or difficulty moving; difficulties with coordination and balance; problems in speech or swallowing (), visual ...
Solitary sclerosis: This variant was proposed (2012) by Mayo Clinic researchers. [ 58 ] though it was also reported by other groups more or less at the same time. [ 59 ] [ 60 ] It is defined as isolated demyelinating lesions which produce a progressive myelopathy similar to primary progressive MS.
Multiple sclerosis (MS) is a neurodegenerative disease in which the immune system attacks myelin, a protective covering of nerve fibers in the central nervous system, causing communication problems between the brain and the rest of the body.
Schilder disease or diffuse myelinoclastic sclerosis: is a rare disease that presents clinically as a pseudotumoural demyelinating lesion; and is more common in children. [7] [8] Marburg multiple sclerosis, an aggressive form, also known as malignant, fulminant or acute MS.
Nearly 2.3 million people are estimated to be living with multiple sclerosis around the world, but when Montel Williams received his official diagnosis back in 1999, not much was known about the ...
Because multiple sclerosis causes demyelination of the axons of the central nervous system, it can cause internuclear ophthalmoplegia when medial longitudinal fasciculus axons get demyelinated. [8] This presents as nystagmus and diplopia. [7] Other demyelinating diseases, as well as certain neoplasms and strokes, can also cause the same ...
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