Search results
Results from the WOW.Com Content Network
Because of its antiandrogenic activity, spironolactone can cause breast tenderness, gynecomastia (breast development), feminization in general, and demasculinization, as well as sexual dysfunction including loss of libido and erectile dysfunction, although these side effects are usually confined to high doses of spironolactone. [109]
Androgen receptor antagonistic potency of spironolactone, cyproterone acetate, and flutamide in castrated male rats treated with exogenous testosterone (as measured by inhibition of androgen-dependent ventral prostate weight). [27] Spironolactone is an antagonist of the AR, the biological target of androgens like testosterone and DHT.
Over on the male side, Dr. Primack says that obesity is often the cause of male breast growth. “Male breast growth is often caused by an imbalance of estrogen levels.
Flibanserin [1] and Bremelanotide [3] were developed for raising sexual desire in women, whereas similar conditions in men are treated using medications for sexual dysfunction. [4] On the other hand, down-regulation on libido comes in two approaches: a direct or an indirect mechanism.
Many drugs can cause loss of libido as a side effect. [12] Since a partial cause of the refractory period is the inhibition of dopamine by an orgasm-induced secretion of prolactin, [13] such potent dopamine receptor agonists as cabergoline may help achieve multiple orgasms as well as the retention of sexual arousal for longer periods of time. [13]
Similarly, life events like pregnancy and nursing can cause a fluctuation in hormones, making you more or less horny than usual, explains Dr. Ross. Additionally, pregnant women tend to experience ...
This can be overwhelming, from looking up hair loss treatments to scouring social media. Skip to main content. Sign in. Mail. 24/7 Help. For premium support please call: 800-290-4726 ...
Insufficient or low levels of testosterone in the body can affect the proper functioning of the male reproductive structures and thus lead to decreased secretions or hypospermia. Long-term exposure to drugs with anti-androgen properties (e.g. spironolactone) can also lead to infertility or low volume of semen. [2]