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The causes of schizophrenia that underlie the development of schizophrenia, a psychiatric disorder, are complex and not clearly understood.A number of hypotheses including the dopamine hypothesis, and the glutamate hypothesis have been put forward in an attempt to explain the link between altered brain function and the symptoms and development of schizophrenia.
The causes of schizophrenia may include genetic and environmental factors. [7] Genetic factors include a variety of common and rare genetic variants . [ 21 ] Possible environmental factors include being raised in a city , childhood adversity, cannabis use during adolescence, infections, the age of a person's mother or father , and poor ...
Schizophrenia is a debilitating and often misunderstood disorder that affects up to 1% of the world's population. [1] Although schizophrenia is a heavily studied disorder, it has remained largely impervious to scientific understanding; epigenetics offers a new avenue for research, understanding, and treatment.
'This will turn out to be the most important break in the disease,' the Broad Institute's director Eric Lander said. A root cause of schizophrenia may have finally been found Skip to main content
The basic principle behind psychiatric genetics is that genetic polymorphisms (as indicated by linkage to e.g. a single nucleotide polymorphism) are part of the causation of psychiatric disorders. [1] Psychiatric genetics is a somewhat new name for the old question, "Are behavioral and psychological conditions and deviations inherited?".
The largest most comprehensive genetic study of its kind, involving tests of several hundred single-nucleotide polymorphisms (SNPs) in nearly 1,900 individuals with schizophrenia or schizoaffective disorder and 2,000 comparison subjects, reported in 2008 that there was no evidence of any significant association between the disorders and any of ...
Schizophrenia is caused by a combination of genetic and environmental factors. [6] Research illustrates that schizophrenia is hereditary and is more likely to strike those who carry particular genes. [9] It is believed that those who are susceptible to the disorder are affected by something in their environment.
Compared to other psychological disorders like major depressive disorder (MDD) and generalized anxiety disorder (GAD), schizophrenia has significantly higher heritability. Schizophrenia has been found to present cross-culturally, and it almost always has 0.1% prevalence in a given population, although some studies have cast doubts on this.
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