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Hematopoietic stem-cell transplantation (HSCT) is the transplantation of multipotent hematopoietic stem cells, usually derived from bone marrow, peripheral blood, or umbilical cord blood, in order to replicate inside a patient and produce additional normal blood cells.
Hematopoietic stem cell transplantation (HSCT) is the transplantation of multipotent hematopoietic stem cells, usually derived from bone marrow, peripheral blood, or umbilical cord blood. [16] [17] [13] It may be autologous (the patient's own stem cells are used), allogeneic (the stem cells come from a donor) or syngeneic (from an identical twin).
A bone marrow harvest in progress The preferred sites for the procedure. In a bone marrow transplant, hematopoietic stem cells are removed from a person and infused into another person or into the same person at a later time . If the donor and recipient are compatible, these infused cells will then travel to the bone marrow and initiate blood ...
Bone Marrow Transplantation is a peer-reviewed medical journal covering transplantation of bone marrow in humans. It is published monthly by Nature Research.The scope of the journal includes stem cell biology, transplantation immunology, translational research, and clinical results of specific transplant protocols.
Retrieved from "https://en.wikipedia.org/w/index.php?title=Bone_marrow_transplant&oldid=613210917"
Total body irradiation (TBI) is a form of radiotherapy used primarily as part of the preparative regimen for haematopoietic stem cell (or bone marrow) transplantation.As the name implies, TBI involves irradiation of the entire body, though in modern practice the lungs are often partially shielded to lower the risk of radiation-induced lung injury.
The idea for high-dose chemotherapy (HDC) with autologous bone marrow transplant (ABMT) originated in the 1950s as a leukemia treatment, when E. Donnall Thomas had shown that bone marrow could be harvested from a person and transplanted into the same or another person. [2] It was promoted as a treatment for advanced breast cancer starting in ...
Bone marrow transplant can replace the transplant recipient's immune system with the donor's, and the recipient accepts the new organ without rejection. The marrow's hematopoietic stem cells —the reservoir of stem cells replenishing exhausted blood cells including white blood cells forming the immune system—must be of the individual who ...
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