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  2. Cyclooxygenase-2 inhibitor - Wikipedia

    en.wikipedia.org/wiki/Cyclooxygenase-2_inhibitor

    In the CLASS trial which compared Celebrex 800 mg/day to ibuprofen 2400 mg/day and diclofenac 150 mg/day for osteoarthritis or rheumatoid arthritis for six months, Celebrex was associated with significantly fewer upper gastrointestinal complications (0.44% vs. 1.27%, p = 0.04), with no significant difference in incidence of cardiovascular ...

  3. Celecoxib - Wikipedia

    en.wikipedia.org/wiki/Celecoxib

    Celecoxib, sold under the brand name Celebrex among others, is a COX-2 inhibitor and nonsteroidal anti-inflammatory drug (NSAID). [7] It is used to treat the pain and inflammation in osteoarthritis , acute pain in adults, rheumatoid arthritis , psoriatic arthritis , ankylosing spondylitis , painful menstruation , and juvenile rheumatoid ...

  4. Discovery and development of cyclooxygenase 2 inhibitors

    en.wikipedia.org/wiki/Discovery_and_development...

    [5] [6] It took less than eight years to develop and market the first COX-2 inhibitor, with Celebrex launched in December 1998 and Vioxx launched in May 1999. [7] [8] Celecoxib and other COX-2 selective inhibitors, valdecoxib, parecoxib, and mavacoxib, were discovered by a team at the Searle division of Monsanto led by John Talley.

  5. Say Goodbye To Sciatica Pain By Stretching These Two Muscles

    www.aol.com/goodbye-sciatica-pain-stretching-two...

    4. Figure Four Seated Stretch. How to: Sit on a chair with feet flat on ground. Cross right ankle leg over left thigh. Keep spine straight and hinge forward to feel a stretch in glute and hip.

  6. The best muscle pain relief creams of 2025, according to ...

    www.aol.com/lifestyle/best-muscle-pain-relief...

    Reduced inflammation: "Some creams may contain anti-inflammatory agents like NSAIDs (e.g., diclofenac) that can reduce localized inflammation," Dr. Ayob says. Reduced pain

  7. FDA approves new type of non-opioid pain medication, 1st of ...

    www.aol.com/fda-approves-type-non-opioid...

    The U.S. Food and Drug Administration (FDA) on Thursday approved a new type of prescription pain medication for adults to treat moderate to severe acute pain. The drug, called Journavx ...

  8. Nonsteroidal anti-inflammatory drug - Wikipedia

    en.wikipedia.org/wiki/Nonsteroidal_anti...

    NSAID identification on label of generic ibuprofen, an over-the-counter non-steroidal anti-inflammatory drug. Non-steroidal anti-inflammatory drugs [1] [3] (NSAID) [1] are members of a therapeutic drug class which reduces pain, [4] decreases inflammation, decreases fever, [1] and prevents blood clots.

  9. Acupuncture can help relieve sciatica pain, new ... - AOL

    www.aol.com/acupuncture-help-relieve-sciatica...

    For the trial, 216 individuals with chronic sciatica resulting from a herniated disc were treated either with 10 sessions of acupuncture or 10 sessions of sham acupuncture over a period of 4 weeks.