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A separatory funnel, also known as a separation funnel, separating funnel, or colloquially sep funnel, is a piece of laboratory glassware used in liquid-liquid extractions to separate (partition) the components of a mixture into two immiscible solvent phases of different densities. [ 1 ] Typically, one of the phases will be aqueous, and the ...
A separatory funnel used for liquid–liquid extraction, as evident by the two immiscible liquids.. Liquid–liquid extraction, also known as solvent extraction and partitioning, is a method to separate compounds or metal complexes, based on their relative solubilities in two different immiscible liquids, usually water (polar) and an organic solvent (non-polar).
The folding funnel hypothesis is a specific version of the energy landscape theory of protein folding, which assumes that a protein 's native state corresponds to its free energy minimum under the solution conditions usually encountered in cells. Although energy landscapes may be "rough", with many non-native local minima in which partially ...
McCabe–Thiele method. The McCabe–Thiele method is a technique that is commonly employed in the field of chemical engineering to model the separation of two substances by a distillation column. [1][2][3] It uses the fact that the composition at each theoretical tray is completely determined by the mole fraction of one of the two components.
Partition coefficient. In the physical sciences, a partition coefficient (P) or distribution coefficient (D) is the ratio of concentrations of a compound in a mixture of two immiscible solvents at equilibrium. This ratio is therefore a comparison of the solubilities of the solute in these two liquids. The partition coefficient generally refers ...
Laboratory funnel. A Büchner funnel with a sintered glass disc. Laboratory funnels are funnels that have been made for use in the chemical laboratory. There are many different kinds of funnels that have been adapted for these specialized applications. Filter funnels, thistle funnels (shaped like thistle flowers), and dropping funnels have ...
t. e. A separation process is a method that converts a mixture or a solution of chemical substances into two or more distinct product mixtures, [ 1 ] a scientific process of separating two or more substances in order to obtain purity. At least one product mixture from the separation is enriched in one or more of the source mixture's constituents.
Work-up. In chemistry, work-up refers to the series of manipulations required to isolate and purify the product (s) of a chemical reaction. [1] The term is used colloquially to refer to these manipulations, which may include: deactivating any unreacted reagents by quenching a reaction. cooling the reaction mixture or adding an antisolvent to ...