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A heart attack occurs suddenly when an atherosclerotic plaque in one of the arteries to your heart ruptures. It can cause symptoms such as: Chest pain, pressure, or tightness
The coronary arteries are the arterial blood vessels of coronary circulation, which transport oxygenated blood to the heart muscle. The heart requires a continuous supply of oxygen to function and survive, much like any other tissue or organ of the body. [1] The coronary arteries wrap around the entire heart.
Plaque is caused by fatty deposits and scar tissue that cling to the walls of coronary arteries. [9] The development of plaque takes years and leads to stenosis of the coronary arteries and progressively reduces blood flow. [8] Due to the slower development of this condition, the body will adapt and create small blood vessels that circumvent ...
The fibro-lipid (fibro-fatty) plaque is characterized by an accumulation of lipid-laden cells underneath the intima of the arteries, typically without narrowing the lumen due to compensatory expansion of the bounding muscular layer of the artery wall. Beneath the endothelium, there is a "fibrous cap" covering the atheromatous "core" of the plaque.
Coronary artery disease develops when the arteries that supply your heart become clogged with a fatty substance called plaque. The build-up of plaque is also called atherosclerosis.
Over time, arteries that carry blood throughout the body get filled with a sticky material called plaque, which is made of materials like cholesterol, calcium and fibrin. To some degree, clogged ...
Foam cells are very small in size and can only be truly detected by examining a fatty plaque under a microscope after it is removed from the body, or more specifically from the heart. Detection usually involves the staining of sections of aortic sinus or artery with Oil Red O (ORO) followed by computer imaging and analysis; or from Nile Red ...
The relatively narrow coronary arteries are commonly affected by atherosclerosis and can become blocked, causing angina or a heart attack. The coronary arteries are classified as "terminal circulation", since they represent the only source of blood supply to the myocardium; there is very little redundant blood supply, that is why blockage of ...
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