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Ciguatera fish poisoning (CFP), also known as ciguatera, is a foodborne illness caused by eating reef fish contaminated with ciguatoxins. [ 4 ] [ 2 ] Such individual fish are said to be ciguatoxic . Symptoms may include diarrhea , vomiting, numbness, itchiness, sensitivity to hot and cold, dizziness , and weakness.
Such poisoning from ciguatoxins is known as ciguatera. Ciguatoxins are lipophilic , able to cross the blood–brain barrier , and can cause both central and peripheral neurologic symptoms. The major symptoms will develop within 1–3 hours of toxin ingestion: vomiting, diarrhea, numbness of extremities, mouth and lips, reversal of hot and cold ...
Even though ciguatera causes major gastrointestinal issues, so far P-CTX-1 hasn't been proven to have a direct effect on digestive systems. Terao et al showed that no morphological alterations were observed in the mucosa or muscle layers of the small intestine , despite the severe diarrhoea commonly observed upon P-CTX-1 administration. [ 25 ]
Gambierdiscus toxicus is a species of photosynthetic unicellular eukaryote belonging to the Alveolata, part of the SAR supergroup.It is a dinoflagellate which can cause the foodborne illness ciguatera, [1] and is known to produce several natural polyethers including ciguatoxin, maitotoxin, gambieric acid, and gambierol.
The bacteria is usually only found in the mouth, far from the colon. In the mouth, it’s one of the most common types of disease-causing bacteria , linked to gum disease and plaque buildup.
Afterwards, carnivorous fish, which are targeted by fishing industries, move the toxins further up the food chain. Ciguatera is the most common form of seafood poisoning caused by harmful algal blooms in the world and its incidence and range appear to spread. Best estimates indicate that more than 50,000 people are globally affected every year.
Isolated reports of scombroid food poisoning in humans caused by histamine present in the tissues of stale or rotten scombroid fish, usually tuna, have occurred over the years. In September 2016, authorities in Singapore intercepted canned tuna imported from Thailand after finding high levels of histamine. [12] No human cases were reported.
About 38 million Americans are afflicted with migraines -- but the medical community has found it difficult to pinpoint what causes them.