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Oxygen is exchanged for carbon dioxide at the blood–air barrier between the alveolar air and the pulmonary capillary. [2] Alveoli make up the functional tissue of the mammalian lungs known as the lung parenchyma, which takes up 90 percent of the total lung volume. [3] [4]
In the lungs, oxygen from the inhaled air is transferred into the blood and circulated throughout the body. Carbon dioxide (CO 2) is transferred from returning blood back into gaseous form in the lungs and exhaled through the lower respiratory tract and then the upper, to complete the process of breathing.
The process of breathing does not fill the alveoli with atmospheric air during each inhalation (about 350 ml per breath), but the inhaled air is carefully diluted and thoroughly mixed with a large volume of gas (about 2.5 liters in adult humans) known as the functional residual capacity which remains in the lungs after each exhalation, and ...
The two types of cell are known as type I and type II cells [32] (also known as pneumocytes). [3] Types I and II make up the walls and alveolar septa. Type I cells provide 95% of the surface area of each alveoli and are flat ("squamous"), and Type II cells generally cluster in the corners of the alveoli and have a cuboidal shape. [33]
If more carbon dioxide than usual has been lost by a short period of hyperventilation, respiration will be slowed down or halted until the alveolar partial pressure of carbon dioxide has returned to 5.3 kPa (40 mmHg). It is therefore strictly speaking untrue that the primary function of the respiratory system is to rid the body of carbon ...
This blood–air barrier is extremely thin (approximately 600 nm-2μm; in some places merely 200 nm) to allow sufficient oxygen diffusion, yet it is extremely strong. This strength comes from the type IV collagen in between the endothelial and epithelial cells. Damage can occur to this barrier at a pressure difference of around 40 millimetres ...
Bronchial arteries carry oxygenated blood to the lungs; Pulmonary capillaries, where there is exchange of water, oxygen, carbon dioxide, and many other nutrients and waste chemical substances between blood and the tissues; Bronchial veins drain venous blood from the large main bronchi into the azygous vein, and ultimately the right atrium.
The pulmonary arteries carry deoxygenated blood to the lungs, where carbon dioxide is released and oxygen is picked up during respiration. [3] Arteries are further divided into very fine capillaries which are extremely thin-walled. [4] The pulmonary veins return oxygenated blood to the left atrium of the heart. [3]