Search results
Results from the WOW.Com Content Network
GLUT1 deficiency syndrome, also known as GLUT1-DS, De Vivo disease or Glucose transporter type 1 deficiency syndrome, is an autosomal dominant genetic metabolic disorder associated with a deficiency of GLUT1, the protein that transports glucose across the blood brain barrier. [1] Glucose Transporter Type 1 Deficiency Syndrome has an estimated ...
Glucose transporter 1 (or GLUT1), also known as solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1), is a uniporter protein that in humans is encoded by the SLC2A1 gene. [1] GLUT1 facilitates the transport of glucose across the plasma membranes of mammalian cells. [ 2 ]
low-affinity glucose transporter [3] Hxt4: Vm = 12.0, Kd = 0.049, Km = 6.2 [1] intermediate-affinity glucose transporter [3] Hxt5: Km = 10 mM [4] Moderate glucose affinity. Abundant during stationary phase, sporulation and low glucose conditions. Transcription repressed by glucose. [4] Hxt6: Vm = 11.4, Kd = 0.029, Km = 0.9/14, [1] 1.5 mM [3 ...
Among them, GLUT1-5 are the most extensively studied. However, for study GLUTs 1-4 or the Class I GLUTs are the most relevant. For more information on other GLUTs see sources 3 and 7, or the GLUT specific wikipedia pages. GLUT1 is a hydrophobic protein and 50% of GLUT1 is in the lipid bilayer.
A glucose transporter (GLUT) protein is needed to assist glucose into (and in the liver and kidneys, also out of) the cell. De Vivo disease (GLUT1 deficiency) is a deficiency of GLUT1, which is needed to transport glucose across the blood-brain barrier.
Its buzzed-about effects on weight and the glut of ... 5.7 percent of patients reported experiencing hair loss versus less than 1 percent on a placebo. So, sure, it’s a possibility, but those ...
Hypoglycorrhachia is associated with Glucose transporter type 1 GLUT1 deficiency syndrome (De Vivo disease). [7] Perhaps a much more common example of the same phenomenon occurs in the people with poorly controlled type 1 diabetes who develop symptoms of hypoglycemia at levels of blood glucose which are normal for most people.
Glutaric acidemia type 1 (GA1) is an inherited disorder in which the body is unable to completely break down the amino acids lysine, hydroxylysine and tryptophan.Excessive levels of their intermediate breakdown products (glutaric acid, glutaryl-CoA, 3-hydroxyglutaric acid, glutaconic acid) can accumulate and cause damage to the brain (and also other organs [1]), but particularly the basal ...