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Pentadecylic acid, also known as pentadecanoic acid or C15:0, is an odd-chain saturated fatty acid. Its molecular formula is CH 3 (CH 2) 13 CO 2 H. It is a colorless solid. A laboratory preparation involves permanganate oxidation of 1-hexadecene (CH 3 (CH 2) 13 CH=CH 2). [2] It is one of the most common odd-chain fatty acids, although it is ...
The side effects of cyproterone acetate (CPA), a steroidal antiandrogen and progestin, including its frequent and rare side effects, have been studied and characterized.It is generally well-tolerated and has a mild side-effect profile, regardless of dosage, when it used as a progestin or antiandrogen in combination with an estrogen such as ethinylestradiol or estradiol valerate in women.
VLCAD (very long-chain-acyl-dehydrogenase) deficiency is exclusively linked to genetic mutations in DNA. A change of the gene that codes for very long-chain-acyl-CoA-dehydrogenase (VLCAD) results in a deficiency or malfunction of the produced VLCAD enzyme. [7] This mutation occurs on chromosome 17 and can be altered via a variety of pathways. [4]
Haemophilia C (also known as plasma thromboplastin antecedent (PTA) deficiency or Rosenthal syndrome) is a mild form of haemophilia affecting both sexes, due to factor XI deficiency. [4] It predominantly occurs in Ashkenazi Jews. It is the fourth most common coagulation disorder after von Willebrand's disease and haemophilia A and B.
With appropriate treatment, most individuals with glucocorticoid deficiency can lead normal lives and have a good prognosis. [4] However, it is important to closely monitor hormone levels and adjust medication accordingly to prevent complications such as adrenal crisis or over-replacement side effects. [1]
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Moderate 21-hydroxylase deficiency is referred to as simple virilizing CAH: Typically is recognized as causing virilization of prepubertal children. Cortisol is reduced, but aldosterone is not. Still milder forms of 21-hydroxylase deficiency are referred to as nonclassical CAH: Can cause androgen effects and infertility in adolescent and adult ...
Pharmacologic treatment in acute situations consists of replacing the enzyme concentrate that is deficient or dysfunctional in this disease process. [20] In life-threatening situations, including cases of oral and pharyngeal swelling, it is important to manage these symptoms and to protect the airways to lower the risk of mortality. [ 20 ]