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Corexit 9500 was designed to replace Corexit 9527. In 2002, Corexit 9527 and Corexit 9500 were the only two chemical dispersants stockpiled in large quantities in the U.S.A. [ 15 ] An estimated 2.5 million gallons of chemicals were used in response to the supertanker SS Torrey Canyon oil spill in the United Kingdom in 1967 . [ 16 ]
A cohort study of almost 2200 Louisiana women found "high physical/environmental exposure was significantly associated with all 13 of the physical health symptoms surveyed, with the strongest associations for burning in nose, throat or lungs ; sore throat; dizziness and wheezing.
Twelve other products received better toxicity and effectiveness ratings, but BP says it chose to use Corexit because it was available the week of the rig explosion. [ 31 ] [ 32 ] Critics contend that the major oil companies stockpile Corexit because of their close business relationship with its manufacturer Nalco .
Negative values of the decimal logarithm of the median lethal dose LD 50 (−log 10 (LD 50)) on a linearized toxicity scale encompassing 11 orders of magnitude. Water occupies the lowest toxicity position (1) while the toxicity scale is dominated by the botulinum toxin (12). [107] The LD 50 values have a very wide range.
The side effects of cyproterone acetate (CPA), a steroidal antiandrogen and progestin, including its frequent and rare side effects, have been studied and characterized.It is generally well-tolerated and has a mild side-effect profile, regardless of dosage, when it used as a progestin or antiandrogen in combination with an estrogen such as ethinylestradiol or estradiol valerate in women.
On the basis of a survey of self-reported minor poisoning carried out in the Asian region, it is estimated that there could be as many as 25 million agricultural workers in the developing world suffering an episode of poisoning each year." [5] In Canada in 2007 more than 6000 cases of acute pesticide poisoning occurred. [40]
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