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  2. Total iron-binding capacity - Wikipedia

    en.wikipedia.org/wiki/Total_iron-binding_capacity

    High. The liver produces more transferrin, presumably attempting to maximize use of the little iron that is available. Low, as there is insufficient iron. Anemia of chronic disease: Low, as the body holds iron intracellularly with ferritin. Low. The body produces less transferrin (but more ferritin), presumably to keep iron away from pathogens ...

  3. Iron tests - Wikipedia

    en.wikipedia.org/wiki/Iron_tests

    Transferrin and TIBC Transferrin saturation Ferritin Transferrin receptor Related tests Hb MCV Iron deficiency anemia: Iron overload (hemochromatosis) * Normal Anemia of chronic disease * * Porphyria cutanea tarda (PCT) Normal Thalassemia Sideroblastic anemia * Megaloblastic anemia: Hemolytic anemia * * * * Pregnancy or use of

  4. Transferrin saturation - Wikipedia

    en.wikipedia.org/wiki/Transferrin_saturation

    Transferrin saturation (TS), measured as a percentage, is a medical laboratory value. It is the value of serum iron divided by the total iron-binding capacity [1] of the available transferrin, the main protein that binds iron in the blood, this value tells a clinician how much serum iron is bound. For instance, a value of 15% means that 15% of ...

  5. Sideroblastic anemia - Wikipedia

    en.wikipedia.org/wiki/Sideroblastic_anemia

    Serum Iron: high; increased ferritin levels; decreased total iron-binding capacity; high transferrin saturation; Hematocrit of about 20-30%; The mean corpuscular volume or MCV is usually normal or low for congenital causes of sideroblastic anemia but normal or high for acquired forms.

  6. Anemia of chronic disease - Wikipedia

    en.wikipedia.org/wiki/Anemia_of_chronic_disease

    In iron deficiency anemia (IDA) ferritin is low. [6] Total iron-binding capacity is high in iron deficiency, reflecting production of more transferrin to increase iron binding; TIBC is low or normal in anemia of chronic inflammation.

  7. Ferritin - Wikipedia

    en.wikipedia.org/wiki/Ferritin

    For this reason, low ferritin levels carry more information than those in the normal range. A falsely low blood ferritin (equivalent to a false positive test) is very uncommon, [35] but can result from a hook effect of the measuring tools in extreme cases. [36] Low ferritin may also indicate hypothyroidism, [37] vitamin C deficiency or celiac ...

  8. Iron overload - Wikipedia

    en.wikipedia.org/wiki/Iron_overload

    Transferrin saturation of greater than 45% combined with an elevated ferritin level is highly sensitive in diagnosing HFE hemochromatosis. [7] Total iron binding capacity may be low in hemochromatosis, but can also be normal. [37]

  9. Iron-deficiency anemia - Wikipedia

    en.wikipedia.org/wiki/Iron-deficiency_anemia

    Iron-deficiency anemia is confirmed by tests that include serum ferritin, serum iron level, serum transferrin, and total iron binding capacity. [59] A low serum ferritin is most commonly found. However, serum ferritin can be elevated by any type of chronic inflammation and thus is not consistently decreased in iron-deficiency anemia. [23]

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