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Leiomyoma enucleated from a uterus. External surface on left; cut surface on right. Micrograph of a small, well-circumscribed colonic leiomyoma arising from the muscularis mucosae and showing fascicles of spindle cells with eosinophilic cytoplasm and elongated, cigar-shaped nuclei Immunohistochemistry for β-catenin in uterine leiomyoma, which is negative as there is only staining of cytoplasm ...
Uterine fibroids, also known as uterine leiomyomas, fibromyoma or fibroids, are benign smooth muscle tumors of the uterus, part of the female reproductive system. [1] Most people [ note 1 ] with fibroids have no symptoms while others may have painful or heavy periods . [ 1 ]
It generally occurs in the metaphysis of long bones in children and adolescents. [2] Typically, there are no symptoms unless there is a fracture . [ 2 ] It can occur as part of a syndrome such as when multiple non-ossifying fibromas occur in neurofibromatosis , or Jaffe–Campanacci syndrome in combination with cafe-au-lait spots , intellectual ...
Benign tumors of bone can be similar macroscopically and require a combination of a clinical history with cytogenetic, molecular, and radiologic tests for diagnosis. [23] Three common forms of benign bone tumors with are giant cell tumor of bone, osteochondroma, and enchondroma; other forms of benign bone tumors exist but may be less prevalent.
Specific genetic alterations may play a role in the development of uterine leiomyomas. A mutation of a single mesenchymal cell, a stem cell that plays an important role in making and repairing bone, and fat – found in the bone marrow and adipose tissues, with the involvement of progesterone and 17 b-estrodiol – can lead to these fibroids. [21]
A teratoma with malignant transformation is a very rare form of teratoma that may contain elements of somatic malignant tumors such as leukemia, carcinoma, or sarcoma. [35] Of 641 children with pure teratoma, nine developed TMT: [47] five carcinoma, two glioma, and two embryonal carcinoma (here, these last are classified among germ cell tumors).
A bone scan uses radioactive tracers, which are injected into your bloodstream. The damaged parts of bones take up more of the tracer, which show up more brightly on the scan. A biopsy, which uses a hollow needle to remove a small piece of the affected bone for laboratory analysis, can diagnose fibrous dysplasia definitely. [citation needed]
Epulis is also sometimes used synonymously with epulis fissuratum, [1] however other conditions are classified as epulides, e.g. giant cell epulis (peripheral giant cell granuloma), ossifying fibroid epulis (peripheral ossifying fibroma), and congenital epulis.