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A benefit of casirivimab and imdevimab treatment has not been shown in people hospitalized due to COVID‑19. [9] Monoclonal antibodies, such as casirivimab and imdevimab, may be associated with worse clinical outcomes when administered to hospitalized people with COVID‑19 requiring high flow oxygen or mechanical ventilation. [9]
Regdanvimab, sold under the brand name Regkirona, is a human monoclonal antibody used for the treatment of COVID-19. [4] The antibody is directed against the spike protein of SARS-CoV-2. It is developed by Celltrion. [7] [8] The medicine is given by infusion (drip) into a vein. [4] [9]
Sotrovimab, sold under the brand name Xevudy, is a human neutralizing monoclonal antibody with activity against severe acute respiratory syndrome coronavirus 2, known as SARS-CoV-2. [10] [12] [13] It was developed by GlaxoSmithKline and Vir Biotechnology, Inc. [12] [14] Sotrovimab is designed to attach to the spike protein of SARS-CoV-2. [12 ...
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A state of the art review published in 2022 stated that the basic principles of diagnosing and managing COVID-19 should be the same for pregnant patients as for non-pregnant patients. It recommnended that treatment with corticosteroids should be modified to use non-fluorinated glucocorticoids and that Il-6 inhibitors and monoclonal antibodies ...
Pregnant women who get an mRNA vaccine against COVID-19 pass high levels of protective antibodies on to their babies, new research shows. Doctors analyzed umbilical cord blood from 36 newborns ...
This list of over 500 monoclonal antibodies includes approved and investigational drugs as well as drugs that have been withdrawn from market; consequently, the column Use does not necessarily indicate clinical usage. See the list of FDA-approved therapeutic monoclonal antibodies in the monoclonal antibody therapy page.
Getting vaccinated during pregnancy, she added, tends to give newborns higher antibody levels than a Covid infection in pregnancy does, so even pregnant mothers who get Covid should get the shot ...