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Periorbital cellulitis, or preseptal cellulitis, is an inflammation and infection of the eyelid and portions of skin around the eye anterior to the orbital septum. [1] It may be caused by breaks in the skin around the eye, and subsequent spread to the eyelid; infection of the sinuses around the nose (); or from spread of an infection elsewhere through the blood.
Orbital septum acts as a physical barrier that prevents the infection of the anterior part of the eye spreading posteriorly. For example, preseptal cellulitis mainly infects the eyelids, anterior to the orbital septum. Meanwhile, orbital cellulitis is located posterior the orbital septum, due to infections spreading from the ethmoidal sinuses.
Cefadroxil is a first-generation cephalosporin antibacterial drug that is the para-hydroxy derivative of cephalexin, and is used similarly in the treatment of mild to moderate susceptible infections such as the bacterium Streptococcus pyogenes, causing the disease popularly called strep throat or streptococcal tonsillitis, urinary tract infection, reproductive tract infection, and skin infections.
Around 95% of people are better after 7 to 10 days of treatment. [2] Those with diabetes, however, often have worse outcomes. [10] Cellulitis occurred in about 21.2 million people in 2015. [7] In the United States about 2 of every 1,000 people per year have a case affecting the lower leg. [1] Cellulitis in 2015 resulted in about 16,900 deaths ...
[8] [9] [10] It was first marketed in 1969 under the brand name Keflex. [11] [12] It is available as a generic medication. [4] [13] It is on the World Health Organization's List of Essential Medicines. [14] In 2022, it was the 101st most commonly prescribed medication in the United States, with more than 6 million prescriptions.
β-Lactam antibiotics are indicated for the prevention and treatment of bacterial infections caused by susceptible organisms. At first, β-lactam antibiotics were mainly active only against gram-positive bacteria, yet the recent development of broad-spectrum β-lactam antibiotics active against various gram-negative organisms has increased their usefulness.
Erysipelas, a bacterial infection which primarily affects superficial dermis, and often involves superficial lymphatics. [10] Unlike cellulitis, it does not affect deeper layers of the skin. It is primarily caused by the Group A beta-hemolytic streptococci, with Streptococcus pyogenes being the most common pathogen. [10]
Cefazolin, also known as cefazoline and cephazolin, is a first-generation cephalosporin antibiotic used for the treatment of a number of bacterial infections. [2] Specifically it is used to treat cellulitis , urinary tract infections , pneumonia , endocarditis , joint infection , and biliary tract infections . [ 2 ]
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