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Fibrocystic changes include fibroadenomas, fibrosis, papillomas of the breast, [1] and apocrine-type metaplasia. [4] Management may involve education about the condition, using a well fitting bra, and pain medication, if needed. [1] Occasionally danazol or tamoxifen may be used for pain. [1]
Micrograph showing apocrine metaplasia of the breast with typical features, [4] including apical snouts with eosinophilic granules. H&E stain. Apocrine metaplasia is a reversible transformation of cells to an apocrine phenotype. It is common in the breast in the context of fibrocystic change. It is seen in women mostly over the age of 50 years.
English: Histopathology of apocrine metaplasia of breast with typical features, H&E stain. Date: 1 February 2024: ... Apocrine; Fibrocystic breast changes; Metaplasia;
Breast pain, nipple discharge, or skin changes may be present. [1] Concerning findings include masses that are hard, do not move easily, are of an irregular shape, or are firmly attached to surrounding tissue. [2] Causes include fibrocystic change, fibroadenomas, breast infection, galactoceles, and breast cancer. [1]
Duct ectasia syndrome is a synonym for nonpuerperal mastitis, but the term has also been occasionally used to describe special cases of fibrocystic diseases or mastalgia or as a wastebasket definition of benign breast disease. Correlation of duct widening with the "classical" symptoms of duct ectasia syndrome is unclear.
Micrograph showing apocrine metaplasia of the breast with typical features [3] H&E stain. Barrett's esophagus is an abnormal change in the cells of the lower esophagus, thought to be caused by damage from chronic stomach acid exposure. The following table lists some common tissues susceptible to metaplasia, and the stimuli that can cause the ...
Lobular carcinoma in situ (LCIS) is an incidental microscopic finding with characteristic cellular morphology and multifocal tissue patterns. The condition is a laboratory diagnosis and refers to unusual cells in the lobules of the breast. [1]
Invasive carcinomas consisting of 10%–90% apocrine tumor tissue have been termed apocrine-like invasive carcinoma; these carcinomas sometime have estrogen receptor-positive [1] and/or progesterone receptor-positive tumor cells. [9] Both of these carcinomas are described in the last section (Other types of apocrine carcinomas) of this article.