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In approximately one-third of these cases the man is the factor, in one third the woman is the factor, and in the remaining third the infertility is a product of factors on both parts. In many lower-income countries, estimating infertility is difficult due to incomplete information and infertility and childlessness stigmas .
20-30% percent of infertility cases are due to male infertility, 20–35% are due to female infertility, and 25-40% are due to combined problems. [13] In 10–20% of cases, no cause is found. [13] The most common cause of female infertility is ovulatory problems, which generally manifest themselves by sparse or absent menstrual periods. [60]
Causes or factors of female infertility can basically be classified regarding whether they are acquired or genetic, or strictly by location.. Although factors of female infertility can be classified as either acquired or genetic, female infertility is usually more or less a combination of nature and nurture.
About 10–15% of human couples are infertile, unable to conceive.In approximately in half of these cases, the underlying cause is related to the male. The underlying causative factors in the male infertility can be attributed to environmental toxins, systemic disorders such as, hypothalamic–pituitary disease, testicular cancers and germ-cell aplasia.
The following will cover the advancements of female fertility agents, major causes of female infertility. Next, it emphasizes on common female fertility agents in terms of their mechanism of action, side effects, fetal consideration and clinical application and ended up by the introduction of supplements and herbal medicines for female infertility.
James Joyce (2 February 1882 – 13 January 1941) was an Irish novelist, poet and literary critic.He contributed to the modernist avant-garde movement and is regarded as one of the most influential and important writers of the 20th century.
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[3] 15-30% of male factor infertility cases can be correlated with genetic abnormalities. [5] One of the most commonly identified genetic abnormalities in male factor infertility are microdeletions on the long arm of the Y chromosome (Yq), specifically at a region known as the azoospermic factor (AZF) region. [3]