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Mitomycin C, an aziridine, is used as a chemotherapeutic agent by virtue of its antitumour activity. [1]In organic chemistry, aziridines are organic compounds containing the aziridine functional group (chemical structure (R−) 4 C 2 N−R), a three-membered heterocycle with one amine (>NR) and two methylene bridges (>CR 2).
Aziridine is an organic compound consisting of the three-membered heterocycle C 2 H 5 N. [ 5 ] [ 6 ] It is a colorless, toxic, volatile liquid that is of significant practical interest. [ 7 ] Aziridine was discovered in 1888 by the chemist Siegmund Gabriel . [ 8 ]
The aziridine ring system of the amino acid is formed by reaction with diisopropyl azodicarboxylate and triphenylphosphane (A type of Mitsunobu reaction). All protecting groups are then removed by reaction with propylamine in dichloromethane to give the final product.
This listing is limited to those independent companies and subsidiaries notable enough to have their own articles in Wikipedia. Both going concerns and defunct firms are included, as well as firms that were part of the pharmaceutical industry at some time in their existence, provided they were engaged in the production of human (as opposed to veterinary) therapeutics.
Polyethylenimine (PEI) or polyaziridine is a polymer with repeating units composed of the amine group and two carbon aliphatic CH 2 CH 2 spacers. Linear polyethyleneimines contain all secondary amines, in contrast to branched PEIs which contain primary, secondary and tertiary amino groups.
Pages in category "Aziridines" The following 13 pages are in this category, out of 13 total. This list may not reflect recent changes. ...
Chemical & Engineering News publishes an annual list of the world's largest chemical producers by sales, excluding formulated products such as pharmaceutical drugs and coatings. [1] In 2018, sales of the top fifty companies amounted to US$ 951,000,000,000, an increase of 11.8% compared to the top fifty producers of 2017. [ 2 ]
This chemical is used in the paper, textile, rubber and pharmaceutical industries. Propyleneimine is also used in making paint. The top global producers of this specialty chemical include DuPont, Mitsubishi Chemical Holdings Corporation, Sigma-Aldrich, Dixie Chemical Company, J and K Scientific, Apollo Scientific, Mitsui Chemicals.