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Experiments with pharmacological agents that cause depletion of monoamines have shown that this depletion does not cause depression in healthy people. [ 61 ] [ 62 ] Another problem that presents is that drugs that deplete monoamines may actually have antidepressants properties.
Nortriptyline may cause problems if taken during pregnancy. [8] Use during breastfeeding appears to be relatively safe. [7] It is a tricyclic antidepressant (TCA) and is believed to work by altering levels of serotonin and norepinephrine. [8] Nortriptyline was approved for medical use in the United States in 1964. [8]
[5] [8] It is unclear if use during pregnancy or breastfeeding is safe. [9] Desvenlafaxine was approved for medical use in the United States in 2008. [5] In Europe its application for use was denied in 2009. [6] In 2022, it was the 208th most commonly prescribed medication in the United States, with more than 1 million prescriptions. [10] [11]
Vitamin B12 supplements might be better for folks with metabolic syndrome or those who have a deficiency. More research is needed to know if vitamin B12 is an effective weight loss aid.
A 2014 meta analysis found no increased risk of persistent pulmonary hypertension associated with exposure to SSRI's in early pregnancy and a slight increase in risk associates with exposure late in pregnancy; "an estimated 286 to 351 women would need to be treated with an SSRI in late pregnancy to result in an average of one additional case of ...
Antidepressants are a common group of medications that help treat several mental health conditions. Doctors need to consider potential side effects when prescribing specific antidepressants.
Antidepressants, including SSRIs, can cross the placenta and have the potential to affect the fetus and newborn, including an increased chance of miscarriage, presenting a dilemma for pregnant women to decide whether to continue to take antidepressants at all, or if they do, considering if tapering and discontinuing during pregnancy could have ...
While intimate problems can happen with any antidepressant drug, certain ones may be more likely to cause ED. This includes citalopram, sertraline, fluoxetine, paroxetine and escitalopram.