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Occupational heat stress is the net load to which a worker is exposed from the combined contributions of metabolic heat, environmental factors, and clothing worn, which results in an increase in heat storage in the body. [1] Heat stress can result in heat-related illnesses, such as heat stroke, hyperthermia, heat exhaustion, heat cramps, heat ...
Physical hazards include ergonomic hazards, radiation, heat and cold stress, vibration hazards, and noise hazards. [1] Engineering controls are often used to mitigate physical hazards. [2] Physical hazards are a common source of injuries in many industries. [3]
Heat shock proteins (HSPs) are a family of proteins produced by cells in response to exposure to stressful conditions. They were first described in relation to heat shock, [1] but are now known to also be expressed during other stresses including exposure to cold, [2] UV light [3] and during wound healing or tissue remodeling. [4]
Heat stress can decrease athletic performance and increase risk for heat illness, which is a type of exertional heat stroke and the leading cause of death of young athletes in the US, says Dr ...
Heat stroke or heatstroke, also known as sun-stroke, is a severe heat illness that results in a body temperature greater than 40.0 °C (104.0 °F), [4] along with red skin, headache, dizziness, and confusion. [2] Sweating is generally present in exertional heatstroke, but not in classic heatstroke. [5] The start of heat stroke can be sudden or ...
The general pathway to thermotolerance is characterized by sensing of heat stress, activation of HSFs, upregulation of heat response, and return to the non-stressed state. [ 7 ] In 2011, while studying heat stress A. thaliana , Ikeda et al. concluded that the early response is regulated by HsfA1 and the extended response is regulated by HsfA2.
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Heat shock proteins induced by the HSR can help prevent protein aggregation that is associated with common neurodegenerative diseases such as Alzheimer's, Huntington's, or Parkinson's disease. [8] The diagram depicts actions taken when a stress is introduced to the cell. Stress will induce HSF-1 and cause proteins to misfold.