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Urinary tract infection in pediatric patients is a significant clinical issue, affecting approximately 7% of fevered infants and children. [43] If left untreated, the infection can ascend from the bladder to the kidneys, resulting in acute pyelonephritis, which leads to hypertension , kidney scarring , and end-stage kidney disease .
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It is used to treat complicated intra-abdominal infections, urinary tract infections, and pneumonia. [4] [5] It is only recommended when other options are not appropriate. [4] It is given by infusion into a vein. [4] Common side effect include nausea, fever, liver problems, headache, trouble sleeping, and pain at the site of infusion. [4]
As of 2010 it was recommended by the IDSA as a first-line treatment option for catheter-associated urinary tract infections in adults. [16] In combination with metronidazole it is recommended as one of several first-line treatment options for adult patients with community-acquired intra-abdominal infections of mild-to-moderate severity. [ 17 ]
Imipenem/cilastatin, sold under the brand name Primaxin among others, is an antibiotic useful for the treatment of a number of bacterial infections. [1] It is made from a combination of imipenem and cilastatin. [1] Specifically it is used for pneumonia, sepsis, endocarditis, joint infections, intra-abdominal infections, and urinary tract ...
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