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Image of CD4 co-receptor binding to MHC (Major Histocompatibility Complex) non-polymorphic region. In molecular biology, CD4 (cluster of differentiation 4) is a glycoprotein that serves as a co-receptor for the T-cell receptor (TCR). CD4 is found on the surface of immune cells such as helper T cells, monocytes, macrophages, and dendritic cells.
Canine epileptoid cramping syndrome (CECS), previously known as Spike's disease, is a hereditary dog disease initially found in Border Terriers and has since been documented in many other dog breeds including Labrador Retrievers and Chihuahuas, with similarities to canine epilepsy. Its cause is unknown. [1]
Skin conditions in dogs are very common, so it's important to recognize the symptoms and understand the factors that cause them. Dr. Rebecca MacMillan, a vet with over 15 years of experience, says ...
A dog with skin irritation and hair loss on its leg caused by demodectic mange. Infectious skin diseases of dogs include contagious and non-contagious infections or infestations. Contagious infections include parasitic, bacterial, fungal and viral skin diseases. One of the most common contagious parasitic skin diseases is Sarcoptic mange (scabies).
Shaker syndrome in dogs is more common in certain breeds - here's what you need to know.
Up to 80 percent of dogs infected will have symptoms, but the mortality rate is only 5 to 8 percent. [5] Infectious canine hepatitis is a sometimes fatal infectious disease of the liver. [6] Canine herpesvirus is an infectious disease that is a common cause of death in puppies less than three weeks old. [7]
A congenital disorder of glycosylation (previously called carbohydrate-deficient glycoprotein syndrome) is one of several rare inborn errors of metabolism in which glycosylation of a variety of tissue proteins and/or lipids is deficient or defective. Congenital disorders of glycosylation are sometimes known as CDG syndromes.
The depletion of CD4 T cells and the development of chronic inflammation are signature processes in HIV pathogenesis that propel progression to acquired immune deficiency syndrome (AIDS). CD4 T cell depleted to the cell count of less than 200cell/μL in blood during AIDS allows various pathogens to escape T cell recognition, thus allowing ...