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Telophase accounts for approximately 2% of the cell cycle's duration. Cytokinesis typically begins before late telophase [1] and, when complete, segregates the two daughter nuclei between a pair of separate daughter cells. Telophase is primarily driven by the dephosphorylation of mitotic cyclin-dependent kinase (Cdk) substrates. [2]
This is an accepted version of this page This is the latest accepted revision, reviewed on 26 January 2025. Cell division producing haploid gametes For the figure of speech, see Meiosis (figure of speech). For the process whereby cell nuclei divide to produce two copies of themselves, see Mitosis. For excessive constriction of the pupils, see Miosis. For the parasitic infestation, see Myiasis ...
The eukaryotic cell cycle consists of four distinct phases: G 1 phase, S phase (synthesis), G 2 phase (collectively known as interphase) and M phase (mitosis and cytokinesis). M phase is itself composed of two tightly coupled processes: mitosis, in which the cell's nucleus divides, and cytokinesis, in which the cell's cytoplasm and cell membrane divides forming two daughter cells.
Animal cell telophase and cytokinesis. Animal cell cytokinesis begins shortly after the onset of sister chromatid separation in the anaphase of mitosis. The process can be divided to the following distinct steps: anaphase spindle reorganization, division plane specification, actin-myosin ring assembly and contraction, and abscission. [5]
The restriction point (R) in the G 1 phase is different from a checkpoint because it does not determine whether cell conditions are ideal to move on to the next phase, but it changes the course of the cell. After a vertebrate cell has been in the G 1 phase for about three hours, the cell enters a restriction point in which it is decided whether ...
Germ cells, or gametes, undergo meiosis, while somatic cells will undergo mitosis. After the cell proceeds successfully through the M phase, it may then undergo cell division through cytokinesis. The control of each checkpoint is controlled by cyclin and cyclin-dependent kinases. The progression of interphase is the result of the increased ...
An illustration of interphase. The chromatin has not yet condensed, and the cell is undergoing its normal functions. An image of the nucleus of a cell currently in interphase (likely G1). Note: Cytoplasm of this cell or the neighboring cell is not visible (top-left), which is currently in the telophase of mitosis.
In eukaryotes, the cell cycle consists of four main stages: G 1, during which a cell is metabolically active and continuously grows; S phase, during which DNA replication takes place; G 2, during which cell growth continues and the cell synthesizes various proteins in preparation for division; and the M phase, during which the duplicated ...