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  2. Cardiac action potential - Wikipedia

    en.wikipedia.org/wiki/Cardiac_action_potential

    As the membrane potential increases, these channels then close and lock (become inactive). Due to the rapid influx sodium ions (steep phase 0 in action potential waveform) activation and inactivation of these channels happens almost at exactly the same time. During the inactivation state, Na + cannot pass through (absolute refractory period ...

  3. Venous return - Wikipedia

    en.wikipedia.org/wiki/Venous_return

    Skeletal muscle pump: Rhythmical contractions of limb muscles as occurs during normal activity such as walking, running, and swimming, promotes venous return.; Decreased venous capacitance: Sympathetic activation of veins decreases venous compliance, increases vasomotor tone, increases central venous pressure and promotes venous return indirectly by augmenting cardiac output through the Frank ...

  4. Cardiac physiology - Wikipedia

    en.wikipedia.org/wiki/Cardiac_physiology

    The first heart sound S1, is the sound created by the closing of the atrioventricular valves during ventricular contraction and is normally described as "lub". The second heart sound, S2, is the sound of the semilunar valves closing during ventricular diastole and is described as "dub". [1]

  5. Cardiac excitation-contraction coupling - Wikipedia

    en.wikipedia.org/wiki/Cardiac_excitation...

    This rate can be altered, however, by nerves that work to either increase heart rate (sympathetic nerves) or decrease it (parasympathetic nerves), as the body's oxygen demands change. Ultimately, muscle contraction revolves around a charged atom (ion) , calcium (Ca 2+ ) , [ 3 ] which is responsible for converting the electrical energy of the ...

  6. Accelerans nerve - Wikipedia

    en.wikipedia.org/wiki/Accelerans_nerve

    Accelerans nerve forms a part of the sympathetic branch of the autonomic nervous system, and its function is to release noradrenaline at its endings on the heart. The heart beats according to a rhythm set up by the sinus-atrial node or pacemaker, which is located on the right atrium of the heart.

  7. Cardiac pacemaker - Wikipedia

    en.wikipedia.org/wiki/Cardiac_pacemaker

    In heart pacemaker cells, phase 0 depends on the activation of L-type calcium channels instead of the activation of voltage-gated fast sodium channels, which are responsible for initiating action potentials in contractile (non-pacemaker) cells. For this reason, the pacemaker action potential rising phase slope is more gradual than that of the ...

  8. Myocardial contractility - Wikipedia

    en.wikipedia.org/wiki/Myocardial_contractility

    An increase in sympathetic stimulation to the heart increases contractility and heart rate. An increase in contractility tends to increase stroke volume and thus a secondary increase in preload. An increase in preload results in an increased force of contraction by Starling's law of the heart; this does not require a change in contractility.

  9. Heart valve - Wikipedia

    en.wikipedia.org/wiki/Heart_valve

    A heart valve is a biological one-way valve that allows blood to flow in one direction through the chambers of the heart. A mammalian heart usually has four valves. Together, the valves determine the direction of blood flow through the heart. Heart valves are opened or closed by a difference in blood pressure on each side. [1] [2] [3]

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