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  2. Spironolactone - Wikipedia

    en.wikipedia.org/wiki/Spironolactone

    However, recent data suggests that both potassium monitoring and dietary restriction of potassium intake is unnecessary in healthy young women taking spironolactone for acne [125] and in healthy young gender-diverse individuals taking spironolactone for hormone therapy. [127]

  3. Pharmacodynamics of spironolactone - Wikipedia

    en.wikipedia.org/wiki/Pharmacodynamics_of...

    7α-Thiomethylspironolactone, the major active form of spironolactone. It accounts for about 80% of the potassium-sparing effect of spironolactone. [1] [2] [3] Canrenone, the second major active form of spironolactone. It accounts for around 10 to 25% of the potassium-sparing effect of spironolactone. [4

  4. Mineralocorticoid receptor antagonist - Wikipedia

    en.wikipedia.org/wiki/Mineralocorticoid_receptor...

    However, spironolactone is metabolized to three active metabolites, which give it prolonged activity (13.8 – 16. 5 hours). Spironolactone has a long half-life and is excreted 47-51% through kidneys. Patients with chronic kidney disease therefore require close monitoring when taking the drug. Spironolactone is also eliminated through feces (35-41%

  5. Potassium-sparing diuretic - Wikipedia

    en.wikipedia.org/wiki/Potassium-sparing_diuretic

    Potassium-sparing diuretics or antikaliuretics [1] refer to drugs that cause diuresis without causing potassium loss in the urine. [2] They are typically used as an adjunct in management of hypertension, cirrhosis, and congestive heart failure. [3] The steroidal aldosterone antagonists can also be used for treatment of primary hyperaldosteronism.

  6. Canrenone - Wikipedia

    en.wikipedia.org/wiki/Canrenone

    Canrenone is an active metabolite of spironolactone, canrenoic acid, and potassium canrenoate, and is considered to be partially responsible for their effects. [9] It has been found to have approximately 10 to 25% of the potassium-sparing diuretic effect of spironolactone, [ 16 ] whereas another metabolite, 7α-thiomethylspironolactone (7α-TMS ...

  7. 6 Different Kinds of Salt and How to Use Them - AOL

    www.aol.com/6-different-kinds-salt-them...

    Nutritionists reveal the 6 best different kinds of salt, when you should be using them, and how much salt you should be consuming in a day.

  8. Your Cholesterol Could Be A Key Indicator Of Dementia. A ...

    www.aol.com/lifestyle/cholesterol-could-key...

    About one-third of the participants were taking a cholesterol-lowering medication during the study, but no one started or stopped their medication during the follow-up. During six years of yearly ...

  9. Spirolactone - Wikipedia

    en.wikipedia.org/wiki/Spirolactone

    Spirolactones are a class of functional group in organic chemistry featuring a cyclic ester attached spiro to another ring system. The name is also used to refer to a class of synthetic steroids, called steroid-17α-spirolactones, 17α-spirolactosteroids, or simply 17α-spirolactones, which feature their spirolactone group at the C17α position.

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