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  2. Ledipasvir/sofosbuvir - Wikipedia

    en.wikipedia.org/wiki/Ledipasvir/sofosbuvir

    Ledipasvir/sofosbuvir, sold under the trade name Harvoni among others, is a medication used to treat hepatitis C. [8] It is a fixed-dose combination of ledipasvir and sofosbuvir. [8] Cure rates are 94% to 99% in people infected with hepatitis C virus (HCV) genotype 1. [9] Some evidence also supports use in HCV genotype 3 and 4. [9]

  3. Ledipasvir - Wikipedia

    en.wikipedia.org/wiki/Ledipasvir

    Ledipasvir is a drug for the treatment of hepatitis C that was developed by Gilead Sciences. [1] After completing Phase III clinical trials, on February 10, 2014, Gilead filed for U.S. approval of a ledipasvir/sofosbuvir fixed-dose combination tablet for genotype 1 hepatitis C. [2] [3] The ledipasvir/sofosbuvir combination is a direct-acting antiviral agent that interferes with HCV replication ...

  4. Sofosbuvir/velpatasvir/voxilaprevir - Wikipedia

    en.wikipedia.org/wiki/Sofosbuvir/velpatasvir/...

    The second trial compared twelve weeks of treatment with the combination versus treatment with the previously approved drugs sofosbuvir and velpatasvir in adults with genotypes 1, 2, or 3 who had previously failed treatment with sofosbuvir but not an NS5A inhibitor drug. [6]

  5. Sofosbuvir - Wikipedia

    en.wikipedia.org/wiki/Sofosbuvir

    Sofosbuvir is also used with other medications and longer treatment durations, depending on specific circumstances, genotype and cost-effectiveness–based perspective. For example, for the treatment of genotypes 1, 4, 5, and 6 hepatitis C infections, sofosbuvir can be used in combination with the viral NS5A inhibitor ledipasvir. [16]

  6. Hepatitis C - Wikipedia

    en.wikipedia.org/wiki/Hepatitis_C

    Hepatitis C is an infectious disease caused by the hepatitis C virus (HCV) that primarily affects the liver; [2] it is a type of viral hepatitis. [6] During the initial infection period, people often have mild or no symptoms. [1] Early symptoms can include fever, dark urine, abdominal pain, and yellow tinged skin. [1]

  7. Sofosbuvir/velpatasvir - Wikipedia

    en.wikipedia.org/wiki/Sofosbuvir/velpatasvir

    Sofosbuvir/velpatasvir, sold under the brand name Epclusa among others, is a fixed-dose combination medication for the treatment of hepatitis C in adults. [2] [5] [6] [7] It combines sofosbuvir and velpatasvir. [2] [5] [6] It is more than 90% effective for hepatitis C genotypes one through six. [2]

  8. Surge in walking pneumonia affects these high-risk groups ...

    www.aol.com/surge-walking-pneumonia-affects-high...

    Cases of walking pneumonia are spiking across the U.S., according to the CDC. Dr. Marc Siegel speaks with Fox News Digital about common sources, symptoms and treatments.

  9. Viral hepatitis - Wikipedia

    en.wikipedia.org/wiki/Viral_hepatitis

    Hepatitis C virus (HCV) can cause acute and chronic infections that are a major cause of hepatocellular carcinoma (HCC), advanced hepatic fibrosis and cirrhosis. [citation needed] HCC is a major cause of death in patients with chronic HCV infection. Regarding the pathogenesis of HCC associated with HCV, that virus may play direct or indirect roles.

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