Search results
Results from the WOW.Com Content Network
For example, if a monolayer of endothelial cells begins sprouting to form capillaries, angiogenesis is occurring. Vasculogenesis, in contrast, is when endothelial precursor cells (angioblasts) migrate and differentiate in response to local cues (such as growth factors and extracellular matrices) to form new blood vessels. These vascular trees ...
Angiogenesis is the physiological process through which new blood vessels form from pre-existing vessels, [1] [2] [3] formed in the earlier stage of vasculogenesis.
The endothelium (pl.: endothelia) is a single layer of squamous endothelial cells that line the interior surface of blood vessels and lymphatic vessels. [1] The endothelium forms an interface between circulating blood or lymph in the lumen and the rest of the vessel wall.
Neovascularization is the natural formation of new blood vessels (neo-+ vascular + -ization), usually in the form of functional microvascular networks, capable of perfusion by red blood cells, that form to serve as collateral circulation in response to local poor perfusion or ischemia.
Endothelial activation is a proinflammatory and procoagulant state of the endothelial cells lining the lumen of blood vessels. [1] It is most characterized by an increase in interactions with white blood cells (leukocytes), and it is associated with the early states of atherosclerosis and sepsis, among others. [2]
Important for Vasculogenesis, Also needed for angiogenesis during ischemia, inflammation, wound healing, and cancer. [ citation needed ] Activity of VEGF-A, as its name implies, has been studied mostly on cells of the vascular endothelium , although it does have effects on a number of other cell types (e.g., stimulation monocyte / macrophage ...
Get AOL Mail for FREE! Manage your email like never before with travel, photo & document views. Personalize your inbox with themes & tabs. You've Got Mail!
As a result, the promotion of endothelial activation, destabilization, and inflammation are promoted. Its role during angiogenesis depends on the presence of Vegf-a. [9] Serum levels of angiopoietin-2 expression are associated with the growth of multiple myeloma, [18] angiogenesis, and overall survival in oral squamous cell carcinoma. [19]