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Diabetic foot infections (DFIs) typically begin in a wound, most often a neuropathic ulceration. While all wounds are colonized with microorganisms, the presence of infection is defined by ≥2 classic findings of inflammation or purulence.
• Foot ulcer: assess if the foot is ulcer-free • Loss of protective sensation (LOPS): assess with one of the following techniques (see Appendix 1 for details): o Pressure perception: Semmes-Weinstein 10 gram monofilament o Vibration perception: 128 Hz tuning fork
Mild and some moderate infections may be treated with oral antibiotics. Severe infections require intravenous antibiotics. Treatment duration is typically one to two weeks and is longer for...
The management of diabetic foot ulcers, including local wound care, use of mechanical offloading, treatment of infection, and indications for revascularization, are reviewed here. The evaluation of the diabetic foot and specific management of the threatened limb are reviewed separately.
A multinational, multicenter, randomized, double-blinded, placebo-controlled trial to evaluate the efficacy of cyclical topical wound oxygen (TWO2) therapy in the treatment of chronic diabetic foot ulcers: the TWO2 Study.
Recommendation 5: We suggest adequate glycemic control (hemoglobin A1c < 7% with strategies to minimize hypoglycemia) to reduce the incidence of diabetic foot ulcers (DFUs) and infections, with subsequent risk of amputation (Grade 2B). Recommendation 6: We recommend against prophylactic arterial revascularization to prevent DFU (Grade 1C).
The first publication offered a broad general overview of diabetic foot issues, encompassing the etiopathogenesis of complications, screening, and wound classification; management of diabetic foot ulcers (DFUs) and diabetic foot infections (DFIs); recognition and treatment of peripheral artery disease (PAD) and Charcot neuroarthropathy; off ...