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Withdrawal symptoms are dose-dependent with heavier users being more affected than lower-dose addicts. The pharmacological treatment of barbiturate withdrawal is an extended process often consisting of converting the patient to a long-acting benzodiazepine (i.e. Valium), followed by slowly tapering off the benzodiazepine. Mental cravings for ...
Secobarbital (as the sodium salt, originally marketed by Eli Lilly and Company for the treatment of insomnia, and subsequently by other companies as described below, under the brand name Seconal) is a short-acting barbiturate derivative drug that was patented in 1934 in the United States. [3] It possesses anaesthetic, anticonvulsant, anxiolytic ...
Barbiturate dependence. Specialty. Psychiatry, narcology, addiction medicine. Barbiturate dependence develops with regular use of barbiturates. This in turn may lead to a need for increasing doses of the drug to get the original desired pharmacological or therapeutic effect. [1] Barbiturate use can lead to both addiction and physical dependence ...
Barbiturate overdose is poisoning due to excessive doses of barbiturates. [ 8 ] Symptoms typically include difficulty thinking, poor coordination, decreased level of consciousness, and a decreased effort to breathe (respiratory depression). [ 1 ] Complications of overdose can include noncardiogenic pulmonary edema. [ 2 ]
Key:HQBIOVWPIHUNKN-UHFFFAOYSA-L. Tuinal was the brand name of a discontinued combination drug composed of two barbiturate salts (secobarbital sodium and amobarbital sodium) in equal proportions. Tuinal was introduced as a sedative - hypnotic (sleeping pill) medication in the late 1940s by Eli Lilly. It was also used in obstetrics for childbirth ...
Amobarbital (formerly known as amylobarbitone or sodium amytal as the soluble sodium salt) is a drug that is a barbiturate derivative. It has sedative - hypnotic properties. It is a white crystalline powder with no odor and a slightly bitter taste. It was first synthesized in Germany in 1923.
Post-acute withdrawal syndrome (PAWS) is a hypothesized set of persistent impairments that occur after withdrawal from alcohol, [1][2] opiates, benzodiazepines, antidepressants, and other substances. [3][4][5] Infants born to mothers who used substances of dependence during pregnancy may also experience a PAWS. [6][7] While PAWS has been ...
Tapering (medicine) In medicine, tapering is the practice of gradually reducing the dosage of a medication to reduce or discontinue it. Generally, tapering is done is to avoid or minimize withdrawal symptoms that arise from neurobiological adaptation to the drug. [1][2] Prescribed psychotropic drugs that may require tapering due to this ...
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