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Live birth rate are significantly higher with progesterone to assist implantation in ICSI cycles. [24] Also, addition of a GNRH agonist has been estimated to increase success rates. [24] [25] Ultra-high magnification sperm injection (IMSI) has no evidence of increased live birth or miscarriage rates compared to standard ICSI. [26]
In ICSI a magnification of x400 is used, while in IMSI an amplification of x6000 to x10,000 is used, increasing the magnification by a factor of 15. This allows the sperm to be examined in greater detail, including the nucleus which contains the sperm's genetic material.
Live birth rate is the percentage of all cycles that lead to live birth, and is the pregnancy rate adjusted for miscarriages and stillbirths. For instance, in 2007, Canadian clinics reported a live birth rate of 27% with in vitro fertilisation. [5]
When pregnancy is desired, the eggs can be thawed, fertilized, and transferred to the uterus as embryos. The procedure's success rate varies depending on factors such as the individual's age (with higher odds of success in younger individuals), overall health, and genetic factors. The first human birth of oocyte cryopreservation was reported in ...
The United Nations Population Division, part of the DESA - Department of Economic and Social Affairs, [20] ranking list is based on the forecast/prediction for the years 2015-2020 and 2020-2025. [21] [22] Only countries/territories with a population of 100,000 or more in 2019 are included. Rankings are based on the 2015–2020 and 2020-2025 ...
Calendar-based systems determine both pre-ovulatory and post-ovulatory infertility based on cycle history. When used to avoid pregnancy, these systems have higher perfect-use failure rates than symptoms-based systems but are still comparable with barrier methods, such as diaphragms and cervical caps .
Low birth weight. [19] In IVF and ICSI, a risk factor is the decreased expression of proteins in energy metabolism; Ferritin light chain and ATP5A1. [20] Preterm birth. Low birth weight and preterm birth are strongly associated with many health problems, such as visual impairment and cerebral palsy. Children born after IVF are roughly twice as ...
A Cochrane review found that hCG or progesterone given during the luteal phase may be associated with higher rates of live birth or ongoing pregnancy, but that the evidence is not conclusive. [68] Co-treatment with GnRH agonists appears to improve outcomes, [68] by a live birth rate RD of +16% (95% confidence interval +10 to +22%). [69]