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Atherosclerosis [a] is a pattern of the disease arteriosclerosis, [8] characterized by development of abnormalities called lesions in walls of arteries. This is a chronic inflammatory disease involving many different cell types and is driven by elevated levels of cholesterol in the blood. [ 9 ]
The hypothesis, which has been tested and modified from its original formulation, has had a profound impact on atherosclerosis research and vascular biology. Instead of a site for passive accumulation of blood lipids, the artery wall is now seen as a living, reactive tissue capable of mounting an inflammatory response.
Atherosclerosis is often referred to as a silent killer, since symptoms often don’t appear or are minimal until it causes severe cardiovascular disease or other complications. Symptoms of ...
Arteriosclerosis, literally meaning "hardening of the arteries", is an umbrella term for a vascular disorder characterized by abnormal thickening, hardening, and loss of elasticity [3] of the walls of arteries; [4] this process gradually restricts the blood flow to one's organs and tissues and can lead to severe health risks brought on by atherosclerosis, which is a specific form of ...
The build-up of plaque is also called atherosclerosis. Plaque can limit the supply of blood and oxygen to your heart tissue. Many people with early coronary artery disease don’t have any symptoms.
The causes, prevention, and/or treatment of all forms of cardiovascular disease remain active fields of biomedical research, with hundreds of scientific studies being published on a weekly basis. Recent areas of research include the link between inflammation and atherosclerosis [ 200 ] the potential for novel therapeutic interventions, [ 201 ...
Atherosclerosis contributes to coronary thrombosis formation by facilitating blood stasis as well as causing local endothelial injury. [ citation needed ] Due to the large number of cases of myocardial infarction leading to death and disease in the world, there has been extensive study towards the generation of clots specifically in the ...
Coronary artery disease is characterized by heart problems that result from atherosclerosis. [34] Atherosclerosis is a type of arteriosclerosis which is the "chronic inflammation of the arteries which causes them to harden and accumulate cholesterol plaques (atheromatous plaques) on the artery walls". [35]
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