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For people with NASH and end-stage liver disease, liver failure, or liver cancer, liver transplantation is an accepted procedure according to the EASL. [16] People with NASH cirrhosis NASH who are being considered for a liver transplant warrant systematic evaluation for cardiovascular diseases (whether the symptoms are apparent or not). [5]
Generally, diseases outlined within the ICD-10 codes K70-K77 within Chapter XI: Diseases of the digestive system should be included in this category. Subcategories This category has the following 4 subcategories, out of 4 total.
Liver cirrhosis makes it hard for blood to flow in the portal venous system. [39] This resistance creates a backup of blood and increases pressure. [39] This results in portal hypertension. Effects of portal hypertension include: Ascites is a build-up of fluid in the peritoneal cavity in the abdomen [40] An enlarged spleen in 35–50% of cases [6]
Both may progress to cirrhosis of the liver, but the risk is much greater with MASH as opposed to MASLD. At 15 years, 11% of people with MASH develop cirrhosis as opposed to less than 1% with MASLD. [3] All cause mortality in MASH is 25.5 per 1000 person years with a liver specific mortality of 11.7 per 1000 person years.
Less than 10% of people with cirrhotic alcoholic FLD will develop hepatocellular carcinoma, [11] the most common type of primary liver cancer in adults, but up to 45% people with NASH without cirrhosis can develop hepatocellular carcinoma. [12] The condition is also associated with other diseases that influence fat metabolism. [13]
Hepatorenal syndrome is a particular and common type of kidney failure that affects individuals with liver cirrhosis or, less commonly, with fulminant liver failure. [1] The syndrome involves constriction of the blood vessels of the kidneys and dilation of blood vessels in the splanchnic circulation, which supplies the intestines. [ 2 ]
Chronic liver diseases like chronic hepatitis, chronic alcohol abuse or chronic toxic liver disease may cause liver failure and hepatorenal syndrome; fibrosis and cirrhosis of liver; Cirrhosis may also occur in primary biliary cirrhosis. Rarely, cirrhosis is congenital.
Liver disease, occurs in at least 30%; Acute liver failure may occur in the postoperative period, and may lead to death acutely following surgery. Steatosis, "alcoholic" type hepatitis, cirrhosis, occurs in 5%, progresses to cirrhosis and death in 1-2%; Erythema nodosum, non-specific pustular dermatosis; Weber–Christian disease
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