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An example of epistasis is the interaction between hair colour and baldness. A gene for total baldness would be epistatic to one for blond hair or red hair. The hair-colour genes are hypostatic to the baldness gene. The baldness phenotype supersedes genes for hair colour, and so the effects are non-additive.
Epistasis and functional genomics. Epistasis refers to genetic interactions in which the mutation of one gene masks the phenotypic effects of a mutation at another locus. [1] Systematic analysis of these epistatic interactions can provide insight into the structure and function of genetic pathways. Examining the phenotypes resulting from pairs ...
Labrador Retriever coat colour genetics. The three recognised colours of Labrador Retriever (top to bottom): chocolate, black and yellow. The genetic basis of coat colour in the Labrador Retriever has been found to depend on several distinct genes. The interplay among these genes is used as an example of epistasis.
Additive genetic effects occur where expression of more than one gene contributes to phenotype (or where alleles of a heterozygous gene both contribute), and the phenotypic expression of these gene (s) can be said to be the sum of these contributions. Non-additive effects involve dominance or epistasis, and cause outcomes that are not a sum of ...
Epistasis occurs when the expression of one gene is modified by another gene. For example, gene A only shows its effect when allele B1 (at another locus) is present, but not if it is absent. This is one of the ways in which two or more genes may combine to produce a coordinated change in more than one characteristic (for instance, in mimicry).
An example in dog coat genetics is the homozygosity with the allele "e e" on the Extension-locus making it impossible to produce any other pigment than pheomelanin. Although the allele "e" is a recessive allele on the extension-locus itself, the presence of two copies leverages the dominance of other coat colour genes.
Equine coat color genetics determine a horse 's coat color. Many colors are possible, but all variations are produced by changes in only a few genes. Bay is the most common color of horse, [ 2 ] followed by black and chestnut. A change at the agouti locus is capable of turning bay to black, while a mutation at the extension locus can turn bay ...
Transgressive segregation. In genetics, transgressive segregation is the formation of extreme phenotypes, or transgressive phenotypes, observed in segregated hybrid populations compared to phenotypes observed in the parental lines. [1] The appearance of these transgressive (extreme) phenotypes can be either positive or negative in terms of fitness.