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ISSN. 1350-9047 (print) 1476-5403 (web) Links. Journal homepage. Cell Death & Differentiation is a peer-reviewed academic journal published by Springer Nature.
Overview of signal transduction pathways involved in apoptosis. Cell death is the event of a biological cell ceasing to carry out its functions. This may be the result of the natural process of old cells dying and being replaced by new ones, as in programmed cell death, or may result from factors such as diseases, localized injury, or the death of the organism of which the cells are part.
Apoptosis (from Ancient Greek: ἀπόπτωσις, romanized: apóptōsis, lit. 'falling off') is a form of programmed cell death that occurs in multicellular organisms and in some eukaryotic, single-celled microorganisms such as yeast. [1] Biochemical events lead to characteristic cell changes (morphology) and death. [2]
Programmed cell death (PCD; sometimes referred to as cellular suicide[1]) is the death of a cell as a result of events inside of a cell, such as apoptosis or autophagy. [2][3] PCD is carried out in a biological process, which usually confers advantage during an organism's lifecycle. For example, the differentiation of fingers and toes in a ...
Cell-count distribution featuring cellular differentiation for three types of cells (progenitor , osteoblast , and chondrocyte ) exposed to pro-osteoblast stimulus. [1] Cellular differentiation is the process in which a stem cell changes from one type to a differentiated one. [2][3] Usually, the cell changes to a more specialized type.
PDBsum. structure summary. Caspases (c ysteine- asp artic prote ases, c ysteine asp art ases or c ysteine-dependent asp artate-directed prote ases) are a family of protease enzymes playing essential roles in programmed cell death. They are named caspases due to their specific cysteine protease activity – a cysteine in its active site ...
Identification of cell death. Standards for the identification of cell death have changed. Cell death used to be defined and described based on morphology. Now there is a switch in classifying it basing on molecular and genetic definitions. This description is more functional and applies to both in vitro and in vivo, so cell death subroutines ...
Carcinogenesis, also called oncogenesis or tumorigenesis, is the formation of a cancer, whereby normal cells are transformed into cancer cells. The process is characterized by changes at the cellular, genetic, and epigenetic levels and abnormal cell division. Cell division is a physiological process that occurs in almost all tissues and under a ...