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In bioinformatics, BLAST (basic local alignment search tool) [3] is an algorithm and program for comparing primary biological sequence information, such as the amino-acid sequences of proteins or the nucleotides of DNA and/or RNA sequences.
In cell biology, precursor cells—also called blast cells—are partially differentiated, or intermediate, and are sometimes referred to as progenitor cells. A precursor cell is a stem cell with the capacity to differentiate into only one cell type, meaning they are unipotent stem cells .
Comparison of monoblast, promonocyte and monocyte. A typical monoblast is about 12 to 20 μm in diameter, has a nuclear to cytoplasm ratio of 4:1 to 3:1, and, like most myeloid blasts, has a round to oval nucleus with fine chromatin structure.
Currently, there is a tendency to call both forms fibroblasts. The suffix "-blast" is used in cellular biology to denote a stem cell or a cell in an activated state of metabolism. Fibroblasts are morphologically heterogeneous with diverse appearances depending on their location and activity.
The nuclear–cytoplasmic ratio (also variously known as the nucleus:cytoplasm ratio, nucleus–cytoplasm ratio, N:C ratio, or N/C) is a measurement used in cell biology. It is a ratio of the size (i.e., volume) of the nucleus of a cell to the size of the cytoplasm of that cell. [1]
In many organisms including Xenopus and Drosophila, the midblastula transition usually occurs after a particular number of cell divisions for a given species, and is defined by the ending of the synchronous cell division cycles of the early blastula development, and the lengthening of the cell cycles by the addition of the G1 and G2 phases.
The blastocyst is a structure formed in the early embryonic development of mammals.It possesses an inner cell mass (ICM) also known as the embryoblast which subsequently forms the embryo, and an outer layer of trophoblast cells called the trophectoderm.
The division of blastomeres from the zygote allows a single fertile cell to continue to cleave and differentiate until a blastocyst forms. The differentiation of the blastomere allows for the development of two distinct cell populations: the inner cell mass, which becomes the precursor to the embryo, and the trophectoderm, which becomes the precursor to the placenta.