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One can flout the maxim of quality to tell a clumsy friend who has just taken a bad fall that his gracefulness is impressive and obviously mean the complete opposite. Likewise, flouting the maxim of quantity may result in ironic understatement, the maxim of relevance in blame by irrelevant praise, and the maxim of manner in ironic ambiguity. [12]
Lithium is approved by the FDA for the treatment of bipolar disorder and is widely prescribed off-label as a treatment for major depressive disorder, [12] often as an augmentation agent. Lithium is recommended for the treatment of schizophrenic disorders only after other antipsychotics have failed; it has limited effectiveness when used alone.
Leech's generosity maxim states: "Minimize the expression of beliefs that express or imply benefit to self; maximize the expression of beliefs that express or imply cost to self." Unlike the tact maxim, the maxim of generosity focuses on the speaker, and says that others should be put first instead of the self. For example:
This list of over 500 monoclonal antibodies includes approved and investigational drugs as well as drugs that have been withdrawn from market; consequently, the column Use does not necessarily indicate clinical usage. See the list of FDA-approved therapeutic monoclonal antibodies in the monoclonal antibody therapy page.
This is a complete list of clinically approved prescription antidepressants throughout the world, as well as clinically approved prescription drugs used to augment antidepressants or mood stabilizers, by pharmacological and/or structural classification.
This list is not limited to drugs that were ever approved by the FDA. Some of them (lumiracoxib, rimonabant, tolrestat, ximelagatran and ximelidine, for example) were approved to be marketed in Europe but had not yet been approved for marketing in the US, when side effects became clear and their developers pulled them from the market.
The center doesn't actually test drugs itself, although it does conduct limited research in the areas of drug quality, safety, and effectiveness standards. As of the end of 2013, the FDA and its predecessors had approved 1,452 drugs, though not all are still available, and some have been withdrawn for safety reasons. [5]
It also might be interesting to include sections on the different ways of interacting with the maxims: observing a maxim, violating a maxim, and opting out of a maxim (in addition to flouting). As someone previously mentioned, I think it is important to make the distinction between violating and flouting a maxim.