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Vutrisiran, sold under the brand name Amvuttra, is a medication used for the treatment of the polyneuropathy of hereditary transthyretin-mediated (hATTR) amyloidosis in adults. [ 7 ] [ 5 ] [ 8 ] It is a double stranded small interfering RNA (siRNA) (also called RNA interference, or RNAi therapeutic) that interferes with the expression of the ...
Tafamidis, sold under the brand names Vyndaqel and Vyndamax, [5] is a medication used to delay disease progression in adults with certain forms of transthyretin ...
Studies showed tafamidis reduced mortality and hospitalization due to heart failure. [5] Previously, for variant ATTR amyloidosis, liver transplant was the only effective treatment. [5] New therapies include diflunisal, inotersen, and patisiran. Diflunisal binds to misfolded mutant TTR protein to prevent its buildup, like how tafamidis works.
The study involved 655 patients from 87 sites across 26 countries.
(Reuters) -Alnylam Pharmaceuticals said on Monday it would not pursue expanded use of its drug to treat a potentially fatal heart disease in the U.S. after the Food and Drug Administration ...
Abbrev. [1]Meaning [1] Latin (or Neo-Latin) origin [1]; a.c. before meals: a.d., ad, AD right ear auris dextra a.m., am, AM morning: ante meridiem: nocte every night ...
There's growing evidence to suggest that GLP-1 drugs, which include Ozempic's semaglutide, may be useful for treating alcohol use disorder.
Patisiran, sold under the brand name Onpattro, is a medication used for the treatment of polyneuropathy in people with hereditary transthyretin-mediated amyloidosis, [7] a fatal rare disease that is estimated to affect 50,000 people worldwide.
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