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Tertiary dentin (including reparative dentin or sclerotic dentin) is a form of dentin, one of the main component materials of teeth. It forms as a reaction to stimulation, including caries , wear and fractures . [ 1 ]
In the case of reparative dentin, other cells are needed to assume the role of the destroyed odontoblasts. Growth factors, especially TGF-β, [85] are thought to initiate the production of reparative dentin by fibroblasts and mesenchymal cells of the pulp. [86] Reparative dentin is produced at an average of 1.5 μm/day, but can be increased to ...
Cross-section of a tooth. B is dentin. Dentin (/ ˈ d ɛ n t ɪ n / DEN-tin) (American English) or dentine (/ ˈ d ɛ n ˌ t iː n / DEN-teen or / ˌ d ɛ n ˈ t iː n / DEN-TEEN) (British English) (Latin: substantia eburnea) is a calcified tissue of the body and, along with enamel, cementum, and pulp, is one of the four major components of teeth.
In the case of an infection breaching the dentin to or very near the pulp, or in the instance of odontoblast death due to other attack (e.g. chemical or physical), undifferentiated mesenchymal cells can differentiate into odontoblast-like cells which then secrete another type, reparative dentin, underneath the site of attack.
Diagram of tooth anatomy. Dental anatomy is a field of anatomy dedicated to the study of human tooth structures. The development, appearance, and classification of teeth fall within its purview. (The function of teeth as they contact one another falls elsewhere, under dental occlusion.)
Dentin formation, known as dentinogenesis, is the first identifiable feature in the crown stage of tooth development. The formation of dentin must always occur before the formation of enamel. The different stages of dentin formation result in different types of dentin: mantle dentin, primary dentin, secondary dentin, and tertiary dentin. [31]
In animal tooth development, dentinogenesis is the formation of dentin, a substance that forms the majority of teeth.Dentinogenesis is performed by odontoblasts, which are a special type of biological cell on the outer wall of dental pulps, and it begins at the late bell stage of a tooth development.
Tooth development begins at week 6 in utero, in the oral epithelium. The process is divided into three stages: Initiation; Morphogenesis and; Histogenesis [2]; At the end of week 7 i.u., localised proliferations of cells in the dental laminae form round and oval swellings known as tooth buds, which will eventually develop into mesenchymal cells and surround the enamel organ.