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  2. Amygdala - Wikipedia

    en.wikipedia.org/wiki/Amygdala

    Human brain in the coronal orientation. Amygdalae are shown in dark red. The amygdala (/ ə ˈ m ɪ ɡ d ə l ə /; pl.: amygdalae / ə ˈ m ɪ ɡ d ə l i,-l aɪ / or amygdalas; also corpus amygdaloideum; Latin from Greek, ἀμυγδαλή, amygdalē, 'almond', 'tonsil' [1]) is a paired nuclear complex present in the cerebral hemispheres of vertebrates.

  3. Biology of bipolar disorder - Wikipedia

    en.wikipedia.org/wiki/Biology_of_bipolar_disorder

    Regardless of directionality of amygdala abnormalities, as the amygdala plays a central role in emotional systems, these findings support dysfunctional emotional circuits in bipolar. A general reduction in ventrolateral prefrontal cortex activity is observed in bipolar, and is lateralized with regard to mood (i.e., left-depression, right-mania ...

  4. Mechanism of autism - Wikipedia

    en.wikipedia.org/wiki/Mechanism_of_autism

    The amygdala, cerebellum, and many other brain regions have been implicated in autism. [15]Unlike some brain disorders which have clear molecular hallmarks that can be observed in every affected individual, such as Alzheimer's disease or Parkinson's disease, autism does not have a unifying mechanism at the molecular, cellular, or systems level.

  5. Ventromedial prefrontal cortex - Wikipedia

    en.wikipedia.org/wiki/Ventromedial_prefrontal_cortex

    The ventromedial prefrontal cortex (vmPFC) is a part of the prefrontal cortex in the mammalian brain.The ventral medial prefrontal is located in the frontal lobe at the bottom of the cerebral hemispheres and is implicated in the processing of risk and fear, as it is critical in the regulation of amygdala activity in humans. [2]

  6. Amygdalotomy - Wikipedia

    en.wikipedia.org/wiki/Amygdalotomy

    Amygdalotomy, also known as amygdalectomy, is a form of psychosurgery which involves the surgical removal or destruction of the amygdala, or parts of the amygdala.It is usually a last-resort treatment for severe aggressive behavioral disorders and similar behaviors including hyperexcitability, violent outbursts, and self-mutilation.

  7. Brodmann area 25 - Wikipedia

    en.wikipedia.org/wiki/Brodmann_area_25

    This region is extremely rich in serotonin transporters and is considered as a governor for a vast network involving areas like hypothalamus and brain stem, which influences changes in appetite and sleep; the amygdala and insula, which affect the mood and anxiety; the hippocampus, which plays an important role in memory formation; and some parts of the frontal cortex responsible for self ...

  8. Amygdalofugal pathway - Wikipedia

    en.wikipedia.org/wiki/Amygdalofugal_pathway

    The amygdala connects to the thalamus both through the amygdalofugal pathway and through a direct connection to the dorsomedial nucleus of the thalamus. [13] After leaving the substantia innominata , the ventral amygdalofugal pathway continues on a medial path to enter the septal region, the lateral preoptic area , the hypothalamus , and the ...

  9. Amygdala hijack - Wikipedia

    en.wikipedia.org/wiki/Amygdala_hijack

    An amygdala hijack is an emotional response that is immediate, overwhelming, and out of measure with the actual stimulus because it has triggered a much more significant emotional threat. [1] The term, coined by Daniel Goleman in his 1996 book Emotional Intelligence: Why It Can Matter More Than IQ , [ 2 ] is used by affective neuroscientists ...