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Ruxolitinib (sold under the brand names Jakafi and Jakavi among others, and as Opzelura in cream form) is a medication used for the treatment of intermediate or high-risk myelofibrosis, [6] a type of myeloproliferative neoplasm that affects the bone marrow; [11] [12] polycythemia vera, when there has been an inadequate response to or intolerance of hydroxyurea; [6] [13] and steroid-refractory ...
The prescribing information for Jakafi now includes a new recommended starting dose of 5 mg twice daily of Jakafi for patients with baseline platelet counts between 50-100 x 10 9 /L (50,000 to ...
The active valve control system (AVCS) is an automobile variable valve timing technology used by Subaru. It varies the timing of the valves by using hydraulic oil pressure to rotate the camshaft, known as "phasing", [1] in order to provide optimal valve timing for engine load conditions. The system is closed loop using the camshaft sensors ...
An isolation valve is a valve in a fluid handling system that stops the flow of process media to a given location, usually for maintenance or safety purposes. [1] They can also be used to provide flow logic (selecting one flow path versus another), and to connect external equipment to a system. [ 2 ]
The hydraulic actuators respond to changes of pressure or flow and will open/close the valve. Automatic control valves do not require an external power source, meaning that the fluid pressure is enough to open and close them. Flow control valves, a type of automatic control valve, regulate fluid flow by maintaining a predetermined flow rate ...
The Borg-Warner 35 transmission (BW-35) is an automatic transmission produced by the BorgWarner company. This article also applies to variations—the M-36 and M-37. When this article refers to "M-3x" it refers to all models. When model number specific it will use the exact model number. The "3" in the number refers to the specific series of ...
The basic just-over-100 bhp (70 kW) engine for the GTI can be boosted to over 130 hp (97 kW) at the flywheel. For ultimate performance the 1.8 K-series engine, with standard cams or VVC (Variable Valve Control) system can be fitted (these engines are found in the MGF and Lotus Elise sports cars, as well as various Rovers and MGs).
The FB16 direct injection turbocharged (DIT) engine is the first FB-series engine with a turbocharger, and includes direct injection with an auto stop/start system. It is the base engine in the first-generation (2014–20 model years) Subaru Levorg. The Levorg also has an option for a 2.0 litre direct injection turbo engine, the FA20F.