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Dermatophytosis as a cause of alopecia is common in cats, too, and in long-haired varieties, dermatophytic pseudomycetomas may be to blame. [7] Alopecia areata has been studied on mice in laboratories. [8] In horses, human contact with the horse and the rubbing of the saddle across the mane can cause patches of hair loss. [7]
The cause of male-pattern hair loss is a combination of genetics and male hormones; the cause of female pattern hair loss is unclear; the cause of alopecia areata is autoimmune; and the cause of telogen effluvium is typically a physically or psychologically stressful event. [4] Telogen effluvium is very common following pregnancy. [4]
A new study suggests that hairy skin moles contain molecules that promote hair growth, and may therefore offer a possible avenue to treat hair loss. Skin moles that grow hair may offer a treatment ...
In normal mice Agouti is only expressed in the skin during hair growth, but these dominant yellow mutations cause it to be expressed in other tissues including liver, muscle, and fat. [7] The mahogany locus interacts with Agouti and a mutation there can override the pigmentation and body weight effects of lethal yellow.
According to a recently published study on mice, microgravity may have been to blame for the thinning of their skin and disrupted hair growth cycle. As part of the 2009 Space travel impacts skin ...
The myoglobin is filtered by the kidneys, but is toxic to the renal tubular epithelium and so may cause acute kidney injury. [32] It is not the myoglobin itself that is toxic (it is a protoxin), but the ferrihemate portion that is dissociated from myoglobin in acidic environments (e.g., acidic urine, lysosomes). [citation needed]
A nude mouse is a laboratory mouse from a strain with a genetic mutation that causes a deteriorated or absent thymus, resulting in an inhibited immune system due to a greatly reduced number of T cells. The phenotype (main outward appearance) of the mouse is a lack of body hair, which gives it the "nude" nickname.
Agouti-signaling protein is a protein that in humans is encoded by the ASIP gene. [5] [6] It is responsible for the distribution of melanin pigment in mammals.[7] [8] Agouti interacts with the melanocortin 1 receptor to determine whether the melanocyte (pigment cell) produces phaeomelanin (a red to yellow pigment), or eumelanin (a brown to black pigment). [9]