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A liver metastasis is a malignant tumor in the liver that has spread from another organ that is affected by cancer. The liver is a common site for metastatic disease because of its rich, dual blood supply (the liver receives blood via the hepatic artery and portal vein). Metastatic tumors in the liver are 20 times more common than primary liver ...
Lymphatic spread is the most common route of initial metastasis for carcinomas. [8] In contrast, it is uncommon for a sarcoma to metastasize via this route. Localized spread to regional lymph nodes near the primary tumor is not normally counted as a metastasis, although this is a sign of a worse outcome.
In metastatic cases, radiotherapy can be used for palliative care. [72] [73] Proton therapy for unresectable hepatocellular carcinoma was associated with improved survival relative to photon-based radiation therapy which may be driven by decreased incidence of post-treatment liver decompensation. [74]
Liver metastases can cause liver enlargement, pain in the right upper quadrant of the abdomen, fever, and weight loss. [7] Lung tumors often cause the release of body-altering hormones, which cause unusual symptoms, called paraneoplastic syndromes. [7] Inappropriate hormone release can cause dramatic shifts in concentrations of blood minerals.
Histoplasmosis is a fungal infection caused by Histoplasma capsulatum. [2] [3] Symptoms of this infection vary greatly, but the disease affects primarily the lungs. [4] Occasionally, other organs are affected; called disseminated histoplasmosis, it can be fatal if left untreated.
Dogs with increased risk of infection: i.e. those used in sports, competitions, shows, or those kept in kennels can be given two treatments 4 weeks before and 2–4 weeks after the event. Professional dogs: i.e. therapy, rescue, or police dogs: 12 times a year, if excretion of worm eggs is to be excluded.
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The most common malignant neoplasms (cancers) of the liver are metastases; those arising from colorectal cancer are among the most common, and the most amenable to surgical resection. The most common primary malignant tumour of the liver is the hepatocellular carcinoma. Another primary malignant liver tumor is the cholangiocarcinoma.