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  2. Thrombocythemia - Wikipedia

    en.wikipedia.org/wiki/Thrombocythemia

    High platelet counts can occur in patients with polycythemia vera (high red blood cell counts), and is an additional risk factor for complications. [citation needed] A very small number of people report symptoms of erythromelalgia, a burning sensation and redness of the extremities that resolves with cooling, or aspirin or both. [3]

  3. Giant platelet disorder - Wikipedia

    en.wikipedia.org/wiki/Giant_platelet_disorder

    Giant platelet disorder; Two giant platelets (stained purple) are visible in this image from a light microscope (40×) from a peripheral blood smear surrounded by red blood cells. One normal platelet can be seen in the upper left side of the image (purple) and is significantly smaller in size than the red blood cells (stained pink). Specialty ...

  4. Essential thrombocythemia - Wikipedia

    en.wikipedia.org/wiki/Essential_thrombocythemia

    Hydroxycarbamide, interferon-α and anagrelide can lower the platelet count. Low-dose aspirin is used to reduce the risk of blood clot formation unless the platelet count is very high, where there is a risk of bleeding from the disease, and hence this measure would be counter-productive as aspirin-use increases the risk of bleeding. [3] [15 ...

  5. Hemolytic–uremic syndrome - Wikipedia

    en.wikipedia.org/wiki/Hemolytic–uremic_syndrome

    [7] [18] [28] Early signs of systemic complement-mediated TMA include thrombocytopenia (platelet count below 150,000 or a decrease from baseline of at least 25%) [16] and evidence of microangiopathic hemolysis, which is characterized by elevated LDH levels, decreased haptoglobin, decreased hemoglobin, and/or the presence of schistocytes.

  6. Disseminated intravascular coagulation - Wikipedia

    en.wikipedia.org/wiki/Disseminated_intravascular...

    Less common causes include snake bites, frostbite, and burns. [1] There are two main types: acute (rapid onset) and chronic (slow onset). [1] Diagnosis is typically based on blood tests. [2] Findings may include low platelets, low fibrinogen, high INR, or high D-dimer. [2] Treatment is mainly directed towards the underlying condition.

  7. Sticky platelet syndrome - Wikipedia

    en.wikipedia.org/wiki/Sticky_platelet_syndrome

    SPS is diagnosed by demonstrating platelet hyperaggregability. In a lab test called aggregometry, platelet stickiness is stimulated with epinephrine (EPI) and/or adenosine diphosphate (ADP). [12] This test is not possible for patients being treated with acetylsalicylic acid until that substance has sufficiently cleared from their system.

  8. Plateletpheresis - Wikipedia

    en.wikipedia.org/wiki/Plateletpheresis

    In a typical set of rules, a platelet donor must weigh at least 50 kg (110 lb) and have a platelet count of at least 150 x 10 9 /L (150,000 platelets per mm³). [2] One unit has greater than 3×10 11 platelets. Therefore, it takes 2 liters of blood having a platelet count of 150,000/mm³ to produce one unit of platelets.

  9. Mean platelet volume - Wikipedia

    en.wikipedia.org/wiki/Mean_platelet_volume

    Mean platelet volume (MPV) is a machine-calculated measurement of the average size of platelets found in blood and is typically included in blood tests as part of the CBC. Since the average platelet size is larger when the body is producing increased numbers of platelets, the MPV test results can be used to make inferences about platelet ...

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