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Sodium thiosulfate, also spelled sodium thiosulphate, is used as a medication to treat cyanide poisoning, pityriasis versicolor, and to decrease side effects from cisplatin. [ 3 ] [ 4 ] [ 5 ] For cyanide poisoning, it is often used after the medication sodium nitrite and is typically only recommended for severe cases.
Sodium thiosulfate is used in the treatment of cyanide poisoning. [3] It is on the World Health Organization's List of Essential Medicines. [4] [5] Other uses include topical treatment of ringworm and tinea versicolor, [3] [6] and treating some side effects of hemodialysis [7] and chemotherapy.
Sodium nitrite/sodium thiosulfate, sold under the brand name Nithiodote, is a fixed-dose combination medication used as an antidote for cyanide poisoning. [1] It contains sodium thiosulfate and sodium nitrite. [1] It is given by intravenous infusion into a vein. [1] It was approved for medical use in the United States in January 2011. [2]
The United States standard cyanide antidote kit first uses a small inhaled dose of amyl nitrite, followed by intravenous sodium nitrite, followed by intravenous sodium thiosulfate. [33] Hydroxocobalamin was approved for use in the US in late 2006 [ 34 ] and is available in Cyanokit antidote kits. [ 35 ]
Sodium nitrite is used as a medication together with sodium thiosulfate to treat cyanide poisoning. [26] It is recommended only in severe cases of cyanide poisoning and has largely been replaced by use of hydroxocobalamin , [ 27 ] a form of vitamin B12 , but given in much higher doses than needed nutritionally. [ 28 ]
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Amobarbital, one of the chemical compounds that can be used as a truth serum. Sedatives or hypnotics that alter higher cognitive function include ethanol, scopolamine, 3-quinuclidinyl benzilate, potent short or intermediate acting hypnotic benzodiazepines such as midazolam, flunitrazepam, and various short and ultra-short acting barbiturates, including sodium thiopental (commonly known by the ...
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